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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL253702
Molecular formula	C21H25N5O5S
IUPAC name	2-hydroxy-N,N-dimethyl-3-[[4-[(R)-(1-methylcyclopropyl)-(5-methylfuran-2-yl)methyl]imino-1,1-dioxo-1,2,5-thiadiazol-3-yl]amino]benzamide
Molecular weight	459.521
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	2.5
Synonyms	SCHEMBL13406895 2-hydroxy-N,N-dimethyl-3-(4-{[(R)-(1-methyl-cyclopropyl)-(5-methyl-furan-2-yl)-methyl]-amino}-1,1-dioxo-1H-1lambda6-[1,2,5]thiadiazol-3-ylamino)-benzamide BDBM50226994
Inchi Key	ILVQGPFDBAOPEN-KRWDZBQOSA-N
Inchi ID	InChI=1S/C21H25N5O5S/c1-12-8-9-15(31-12)17(21(2)10-11-21)23-19-18(24-32(29,30)25-19)22-14-7-5-6-13(16(14)27)20(28)26(3)4/h5-9,17,27H,10-11H2,1-4H3,(H,22,24)(H,23,25)/t17-/m0/s1
PubChem CID	136036520
ChEMBL	CHEMBL253702
IUPHAR	N/A
BindingDB	50226994
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
561535	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
561536	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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