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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Bufotenine
Molecular formula	C12H16N2O
IUPAC name	3-[2-(dimethylamino)ethyl]-1H-indol-5-ol
Molecular weight	204.273
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.2
Synonyms	NCGC00247724-01 1H-Indol-5-ol, 3-[2-(dimethylamino)ethyl]- STK368137 3-(2-Dimethylaminoethyl)indol-5-ol {3-[(2-Dimethylamino)ethyl]-5-indolol} 3-[2-(Dimethylamino)ethyl]-Indol-5-ol 5-OH-DMT CHEMBL416526 Dimethylserotonin FT-0623282 LS-83677 NSC89593 3-(.beta.-Dimethylaminoethyl)-5-hydroxyindole UNII-0A31347TZK 3-[(2-Dimethylamino)ethyl]-5-indolol 487-93-4 AC1L1UTH C08299 CTK6I0591 DSSTox_CID_28820 INDOL-5-OL, 3-(2-(DIMETHYLAMINO)ETHYL)- Mappine N,N-Dimethyl-5-hydroxytryptamine PDSP2_000007 3-(2-dimethylaminoethyl)-1H-indol-5-ol WLN: T56 BMJ D2N1&1 GQ 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol # 5-Hydroxy-N, N-dimethyltryptamine BRN 0160628 CHEBI:3210 DB01445 DTXSID0048894 KB-56697 NSC 89593 1H-Indol-5-ol, {3-[2-(dimethylamino)ethyl]-} TC-061237 3-(beta-Dimethylaminoethyl)-5-hydroxyindole {3-[(beta-Dimethylamino)ethyl]-5-hydroxyindole} 3-[2-(Dimethylamino)ethyl]indol-5-ol Bufotenine 1.0 mg/ml in Acetonitrile Cinobufotenine DM5-HT GTPL144 Mapine 0A31347TZK Oprea1_475603 3-(2-(Dimethylamino)ethyl)-1H-indol-5-ol VTTONGPRPXSUTJ-UHFFFAOYSA-N 3-[.beta.-(Dimethylamino)ethyl]-5-hydroxyindole 5-22-12-00026 (Beilstein Handbook Reference) AKOS005445162 CAS-487-93-4 D0SP2J DSSTox_GSID_48894 Indol-5-ol, 3-[2-(dimethylamino)ethyl]- N, N-Dimethylserotonin N,N-Dimethylserotonin 1H-Indol-5-ol, 3-(2-(dimethylamino)ethyl)- SCHEMBL518028 3-(2-Dimethylaminoethyl)-5-indolol ZINC1070 3-[2-(Dimethylamino)ethyl]-5-indolol 5-Hydroxy-N,N-dimethyltryptamine Bufotenin DEA No. 7433 EINECS 207-667-9 L001128 NSC-89593 1H-Indol-5-ol,3-[2-(dimethylamino)ethyl]- Tox21_112890 3-[(.beta.-Dimethylamino)ethyl]-5-hydroxyindole 3-[beta-(Dimethylamino)ethyl]-5-hydroxyindole 8-methoxy-2,2,5,6-tetramethyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one Bufotenine solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material Cohoba DMT,5-OH InChI=1/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H Mappin N,N-Dimethyl-5-HT 1,5-benzoxazepin-4(5H)-one, 2,3-dihydro-8-methoxy-2,2,5,6-tetramethyl- PDSP1_000007 3-(2-(Dimethylamino)ethyl)-1H-indol-5-ol (ACD/Name 4.0) VZ36427 3-[2-(Dimethylamino)ethyl]-1H-indol-5-ol 5-hydroxy-dimethyltryptamine BDBM50024206 cebilcin DB-012579 DSSTox_RID_83089 Indol-5-ol, {3-[2-(dimethylamino)ethyl]-} [ Show all ]
Inchi Key	VTTONGPRPXSUTJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
PubChem CID	10257
ChEMBL	CHEMBL416526
IUPHAR	144
BindingDB	50024206
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
364100	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
364108	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
364102	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
364099	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
364113	5-hydroxytryptamine receptor 1F	Q02284	Htr1f	Mus musculus (Mouse)	366
364103	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
364112	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
557003	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
364104	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
364106	5-hydroxytryptamine receptor 5A	P30966	Htr5a	Mus musculus (Mouse)	357
364110	5-hydroxytryptamine receptor 5B	P31387	Htr5b	Mus musculus (Mouse)	370
364101	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
364111	5-hydroxytryptamine receptor 6	Q9R1C8	Htr6	Mus musculus (Mouse)	440
364105	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
364107	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
555094	5-hydroxytryptamine receptor 7	P32304	Htr7	Mus musculus (Mouse)	448

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