You can:
Name | 5-hydroxytryptamine receptor 7 |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | HTR7 |
Synonym | 5-HT-7 5-HT-X 5-HT7 Serotonin receptor 7 |
Disease | N/A for non-human GPCRs |
Length | 446 |
Amino acid sequence | MMGVNSSGRPDLYGHLHSILLPGRGLPDWSPDGGADPGVSTWTPRLLSGVPEVAASPSPSWDGTWDNVSGCGEQINYGRAEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSAAKHKFPGFPRVQPESIISLNGMVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTACSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPECVLQNSDYCRKKGHDS |
UniProt | P50407 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5494 |
IUPHAR | N/A |
DrugBank | N/A |
Name | Bufotenine |
---|---|
Molecular formula | C12H16N2O |
IUPAC name | 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol |
Molecular weight | 204.273 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 2 |
XlogP | 1.2 |
Synonyms | 3-[(.beta.-Dimethylamino)ethyl]-5-hydroxyindole 3-[beta-(Dimethylamino)ethyl]-5-hydroxyindole 8-methoxy-2,2,5,6-tetramethyl-2,3-dihydro-1,5-benzoxazepin-4(5H)-one Bufotenine solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material Cohoba [ Show all ] |
Inchi Key | VTTONGPRPXSUTJ-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3 |
PubChem CID | 10257 |
ChEMBL | CHEMBL416526 |
IUPHAR | 144 |
BindingDB | 50024206 |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 19.95 nM | PMID7518496 | PDSP,BindingDB |
Ki | 21.37 nM | PMID7647964 | PDSP,BindingDB |
Ki | 95.49 nM | PMID7647964 | PDSP,BindingDB |
zhanglabzhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417