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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL125745
Molecular formula	C16H16N2O2S
IUPAC name	2-[1-(benzenesulfonyl)indol-4-yl]ethanamine
Molecular weight	300.376
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.5
Synonyms	1-(Phenylsulfonyl)-4-(2-aminoethyl)-1H-indole BDBM50106251 SCHEMBL739877 2-(1-Benzenesulfonyl-1H-indol-4-yl)-ethylamine ZINC8954
Inchi Key	VNWSJGQXBGKBED-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H16N2O2S/c17-11-9-13-5-4-8-16-15(13)10-12-18(16)21(19,20)14-6-2-1-3-7-14/h1-8,10,12H,9,11,17H2
PubChem CID	9817810
ChEMBL	CHEMBL125745
IUPHAR	N/A
BindingDB	50106251
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
359854	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
359848	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
359850	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
359849	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
359857	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
359853	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
359852	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
359851	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
359847	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
359855	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
359856	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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