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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL126340
Molecular formula	C25H24N2O3S
IUPAC name	[1-(benzenesulfonyl)-4-[2-(dimethylamino)ethyl]indol-2-yl]-phenylmethanone
Molecular weight	432.538
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.2
Synonyms	SCHEMBL6921957 2-Benzoyl-1-(phenylsulfonyl)-4-[2-(dimethylamino)ethyl]-1H-indole [1-Benzenesulfonyl-4-(2-dimethylamino-ethyl)-1H-indol-2-yl]-phenyl-methanone BDBM50106246
Inchi Key	PBBGIYKMAVNTAL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24N2O3S/c1-26(2)17-16-19-12-9-15-23-22(19)18-24(25(28)20-10-5-3-6-11-20)27(23)31(29,30)21-13-7-4-8-14-21/h3-15,18H,16-17H2,1-2H3
PubChem CID	9867475
ChEMBL	CHEMBL126340
IUPHAR	N/A
BindingDB	50106246
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
255409	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
255405	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
255402	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
255408	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
255411	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
255410	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
255412	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
255403	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
255406	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
255407	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
255404	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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