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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SC-52491
Molecular formula	C16H20ClN3O2
IUPAC name	4-amino-N-(1-azatricyclo[3.3.1.03,7]nonan-4-yl)-5-chloro-2-methoxybenzamide
Molecular weight	321.805
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	1.7
Synonyms	SC-52491A CHEMBL558226 4-Amino-N-(1-aza-tricyclo[3.3.1.03,7]non-4-yl)-5-chloro-2-methoxy-benzamide; hydrochloride SC-52490 BDBM50289986 SCHEMBL7304820 147600-74-6 D03TPY CHEMBL319673 175773-85-0 L005147 [ Show all ]
Inchi Key	MRKYTIJPEALHEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H20ClN3O2/c1-22-14-4-13(18)12(17)3-10(14)16(21)19-15-9-2-8-5-20(6-9)7-11(8)15/h3-4,8-9,11,15H,2,5-7,18H2,1H3,(H,19,21)
PubChem CID	9885123
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50289986, 50181836
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
212490	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
212492	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
212489	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
212496	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
212491	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
461074	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
212493	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
212497	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
212495	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
212494	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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