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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Osanetant
Molecular formula	C35H41Cl2N3O2
IUPAC name	N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide
Molecular weight	606.632
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	7.0
Synonyms	[3H]SR142,801 AC1Q3O5K CHEMBL346178 I06-1312 n-(1-{3-[(3r)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl)-n-methylacetamide Osanetant [INN] SR-142,801 (S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine AN-16905 LS-187093 N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidyl]propyl]-4-phenyl-4-piperidyl]-N-methyl-acetamide SB-236984 SR-142806 BRD-K15646852-001-01-5 GTPL2110 N-(1-(3-((3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl)propyl)-4-phenyl-4-piperidinyl)-N-methylacetamide NCGC00263110-02 SR 142,806 ZINC3935475 [3H]SR142801 Acetamide, N-(1-(3-(1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl)propyl)-4-phenyl-4-piperidinyl)-N-methyl-, (R)- D0IP6X K7G81N94DT N-(1-{3-[(R)-1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-4-phenyl-piperidin-4-yl)-N-methyl-acetamide PDSP1_001495 SR-14280 160492-56-8 BCP9001032 DB04872 MLS006010325 N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide SCHEMBL119440 SR142801 AC1L560J GTPL3480 N-(1-(3-((R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidyl)propyl)-4-phenyl-4-piperidyl)-N-methylacetamide SR 142801 [3H]osanetant AKOS015895948 D0M7DJ LS-185126 N-[1-[3-[(3R)-1-(benzoyl)-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide PDSP2_001479 SR-142801 BDBM50291261 FT-0689956 MolPort-006-170-013 NCGC00263110-01 SMR004701389 UNII-K7G81N94DT [ Show all ]
Inchi Key	DZOJBGLFWINFBF-UMSFTDKQSA-N
Inchi ID	InChI=1S/C35H41Cl2N3O2/c1-27(41)38(2)35(29-13-7-4-8-14-29)19-23-39(24-20-35)21-9-17-34(30-15-16-31(36)32(37)25-30)18-10-22-40(26-34)33(42)28-11-5-3-6-12-28/h3-8,11-16,25H,9-10,17-24,26H2,1-2H3/t34-/m0/s1
PubChem CID	219077
ChEMBL	CHEMBL346178
IUPHAR	2110
BindingDB	50291261
DrugBank	DB04872
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
444584	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
444583	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
444587	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
444577	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
444579	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
444585	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
444581	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
444578	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
444586	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
444588	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
444580	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
444582	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
444589	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532
72878	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
72880	Neuromedin-K receptor	P29371	TACR3	Homo sapiens (Human)	465
72881	Neuromedin-K receptor	P30098	TACR3	Cavia porcellus (Guinea pig)	440
72879	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
72882	Substance-K receptor	P16610	Tacr2	Rattus norvegicus (Rat)	390
72877	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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