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| Name | Substance-K receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Tacr2 |
| Synonym | TAC2R Substance K receptor SP-E receptor SKR NKNAR [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 390 |
| Amino acid sequence | MGTRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLSRRVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGEPAGPICKAQA |
| UniProt | P16610 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4554 |
| IUPHAR | 361 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 889 |  CHEMBL439281 | C39H47N7O6S | 741.908 | 8 / 6 | 2.9 | No |
| 2491 |  Substance P | C63H98N18O13S | 1347.65 | 17 / 15 | -2.3 | No |
| 3951 |  CHEMBL441206 | C75H109N19O13 | 1484.82 | 16 / 15 | 0.5 | No |
| 8284 |  CHEMBL565429 | C19H17N3 | 287.366 | 3 / 0 | 3.3 | Yes |
| 11120 |  CHEMBL576844 | C20H17IN2 | 412.274 | 2 / 0 | 4.9 | Yes |
| 11676 |  CHEMBL384541 | C63H96N14O12S | 1273.61 | 15 / 12 | 1.2 | No |
| 16529 |  CHEMBL335248 | C32H53N7O6S | 663.879 | 8 / 7 | 1.4 | No |
| 19024 |  GR-159897 | C23H27FN2O2S | 414.539 | 5 / 1 | 3.4 | Yes |
| 19391 |  CHEMBL566659 | C20H17BrN2 | 365.274 | 2 / 0 | 5.0 | Yes |
| 20473 |  CHEMBL329888 | C46H58N8O11S | 931.075 | 13 / 11 | 0.6 | No |
| 24755 |  CHEMBL439377 | C38H45N7O4 | 663.823 | 6 / 5 | 3.3 | No |
| 27367 |  CHEMBL367542 | C32H37Cl2N3O2 | 566.567 | 3 / 1 | 6.3 | No |
| 29737 |  CHEMBL441454 | C45H66N12O7S | 919.16 | 10 / 10 | 1.1 | No |
| 30740 |  CHEMBL265115 | C49H76N12O9S | 1009.28 | 11 / 10 | 0.9 | No |
| 30744 |  CHEMBL412621 | C60H64N10O12 | 1117.23 | 13 / 14 | 3.2 | No |
| 558249 |  CHEMBL266884 | C41H52N8O7S | 800.976 | 8 / 6 | 2.8 | No |
| 442909 |  CHEMBL3349688 | C41H52N8O7S | 800.976 | 8 / 6 | 2.8 | No |
| 34849 |  CHEMBL262048 | C39H57N7O6S | 751.988 | 8 / 6 | 3.0 | No |
| 34853 |  CHEMBL407511 | C39H57N7O6S | 751.988 | 8 / 6 | 3.0 | No |
| 36217 |  L-732,138 | C22H18F6N2O3 | 472.387 | 9 / 2 | 4.7 | Yes |
| 36401 |  CHEMBL225297 | C39H47N9O7S | 785.921 | 10 / 7 | 1.2 | No |
| 38491 |  CHEMBL436879 | C69H108N18O13S | 1429.8 | 17 / 14 | -0.5 | No |
| 40539 |  MEN-10627 | C38H48N8O7S | 760.911 | 8 / 8 | 2.0 | No |
| 43105 |  CHEMBL157858 | C37H43N5O6 | 653.78 | 6 / 4 | 3.4 | No |
| 44156 |  CHEMBL410808 | C69H102N18O13S | 1423.75 | 17 / 15 | -0.9 | No |
| 49587 |  CHEMBL387199 | C56H64N10O11S | 1085.25 | 13 / 13 | 2.6 | No |
| 49737 |  CHEMBL2370054 | C49H67N9O11 | 958.127 | 11 / 8 | 3.6 | No |
| 49795 |  CHEMBL3144343 | C41H44N6O6 | 716.839 | 6 / 3 | 3.8 | No |
| 558809 |  CHEMBL296267 | C41H44N6O6 | 716.839 | 6 / 3 | 3.8 | No |
| 52027 |  GR 94800 | C49H61N9O8 | 904.082 | 8 / 7 | 4.4 | No |
| 52167 |  CHEMBL224427 | C40H48N8O5 | 720.875 | 7 / 6 | 2.6 | No |
| 52196 |  CHEMBL224003 | C39H45N7O5 | 691.833 | 6 / 5 | 2.8 | No |
| 52309 |  CHEMBL71972 | C28H37Cl2N3O2 | 518.523 | 3 / 0 | 5.5 | No |
| 55675 |  CHEMBL2370069 | C50H71N13O11 | 1030.2 | 12 / 9 | 3.5 | No |
| 56305 |  CHEMBL122169 | C24H25F2N3O2 | 425.48 | 5 / 1 | 4.1 | Yes |
| 57198 |  CHEMBL264341 | C63H96N18O13S | 1345.63 | 17 / 15 | -2.2 | No |
| 57202 |  CHEMBL265573 | C63H96N18O13S | 1345.63 | 17 / 15 | -2.2 | No |
| 57717 |  CHEMBL173049 | C30H39N5O4 | 533.673 | 4 / 4 | 3.6 | No |
| 443969 |  CHEMBL3349531 | C36H47N7O6S | 705.875 | 7 / 7 | 2.8 | No |
| 559071 |  CHEMBL268293 | C36H47N7O6S | 705.875 | 7 / 7 | 2.8 | No |
| 62748 |  CHEMBL1214027 | C72H90F6N12O11S2 | 1477.69 | 20 / 11 | 8.5 | No |
| 62754 |  CHEMBL1214026 | C72H90F6N12O11S2 | 1477.69 | 20 / 11 | 8.5 | No |
| 64621 |  CHEMBL565630 | C16H15ClN2 | 270.76 | 2 / 0 | 3.7 | Yes |
| 64678 |  CHEMBL412189 | C60H64N10O11 | 1101.23 | 12 / 13 | 3.5 | No |
| 64908 |  CHEMBL375214 | C47H57N9O12 | 940.024 | 12 / 12 | -0.7 | No |
| 65562 |  CHEMBL122019 | C24H24F3N3O2 | 443.47 | 6 / 1 | 4.2 | Yes |
| 65978 |  CHEMBL422779 | C42H62N10O7S | 851.081 | 9 / 8 | 1.9 | No |
| 66448 |  CHEMBL173203 | C31H34Cl2N2O3 | 553.524 | 4 / 0 | 6.5 | No |
| 68058 |  CHEMBL264353 | C69H100N18O13S | 1421.73 | 17 / 15 | -1.2 | No |
| 68236 |  CHEMBL327457 | C48H59N9O10S | 954.113 | 12 / 11 | 1.1 | No |
| 70244 |  CHEMBL224009 | C43H53N7O4 | 731.942 | 6 / 5 | 4.9 | No |
| 555759 |  CHEMBL299377 | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 72882 |  Osanetant | C35H41Cl2N3O2 | 606.632 | 3 / 0 | 7.0 | No |
| 73433 |  CHEMBL441181 | C50H60N10O11S | 1009.15 | 13 / 13 | 0.3 | No |
| 73776 |  CHEMBL125001 | C25H28FN3O2 | 421.516 | 4 / 1 | 4.4 | Yes |
| 74963 |  CHEMBL576647 | C20H19NO2 | 305.377 | 3 / 1 | 1.8 | Yes |
| 75868 |  CHEMBL338030 | C28H28FN3O2 | 457.549 | 4 / 1 | 5.2 | No |
| 80402 |  CHEMBL438716 | C48H60N12O11 | 981.081 | 13 / 14 | -1.4 | No |
| 80405 |  CHEMBL266526 | C48H60N12O11 | 981.081 | 13 / 14 | -1.4 | No |
| 80943 |  CHEMBL225588 | C44H54N8O6 | 790.966 | 8 / 6 | 3.1 | No |
| 82532 |  CHEMBL60459 | C23H27FN2O2 | 382.479 | 4 / 2 | 4.2 | Yes |
| 83279 |  CHEMBL172938 | C24H28N4O3 | 420.513 | 3 / 4 | 3.2 | Yes |
| 86450 |  CHEMBL68440 | C30H32Cl2N4O2 | 551.512 | 3 / 1 | 6.5 | No |
| 92016 |  CHEMBL2370058 | C45H63N11O8 | 886.068 | 9 / 8 | 2.1 | No |
| 560208 |  CHEMBL427627 | C42H51N7O7S | 797.972 | 8 / 6 | 3.6 | No |
| 445446 |  CHEMBL3349683 | C42H51N7O7S | 797.972 | 8 / 6 | 3.6 | No |
| 445449 |  CHEMBL3349995 | C40H52N8O8S | 804.964 | 9 / 7 | 1.8 | No |
| 560220 |  CHEMBL414195 | C40H52N8O8S | 804.964 | 9 / 7 | 1.8 | No |
| 94274 |  CHEMBL389432 | C38H45N7O4 | 663.823 | 6 / 6 | 3.1 | No |
| 95052 |  CHEMBL2370050 | C42H67N11O9 | 870.066 | 10 / 8 | 1.2 | No |
| 95439 |  CHEMBL586037 | C28H27NO2 | 409.529 | 3 / 0 | 6.4 | No |
| 96737 |  CHEMBL293580 | C46H58N8O6 | 819.02 | 7 / 6 | 3.9 | No |
| 98761 |  CHEMBL2372521 | C71H102N18O13S | 1447.77 | 17 / 15 | -1.0 | No |
| 101278 |  CHEMBL178959 | C44H69N11O9 | 896.104 | 10 / 7 | 1.5 | No |
| 103237 |  CHEMBL2372516 | C72H104N18O13S | 1461.8 | 17 / 14 | -0.4 | No |
| 103415 |  CHEMBL338825 | C24H27FN4O | 406.505 | 3 / 2 | 3.4 | Yes |
| 445802 |  CHEMBL3349619 | C41H54N8O7S | 802.992 | 8 / 7 | 2.9 | No |
| 560534 |  CHEMBL6241 | C41H54N8O7S | 802.992 | 8 / 7 | 2.9 | No |
| 445803 |  CHEMBL3349990 | C41H54N8O7S | 802.992 | 8 / 7 | 2.9 | No |
| 560535 |  CHEMBL2370528 | C41H54N8O7S | 802.992 | 8 / 7 | 2.9 | No |
| 110949 |  CHEMBL170102 | C26H31N5O4 | 477.565 | 4 / 4 | 1.9 | Yes |
| 112526 |  NEUROKININ A | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 555910 |  Substance K | C50H80N14O14S | 1133.33 | 18 / 16 | -4.8 | No |
| 112587 |  CHEMBL406487 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 112589 |  CHEMBL429340 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 112594 |  CHEMBL217365 | C57H67N13O11 | 1110.24 | 13 / 15 | 0.8 | No |
| 114894 |  CHEMBL390167 | C41H48N8O6 | 748.885 | 7 / 7 | 2.2 | No |
| 560949 |  CHEMBL297376 | C44H48N6O8 | 788.902 | 8 / 4 | 3.2 | No |
| 117951 |  CHEMBL3144351 | C44H48N6O8 | 788.902 | 8 / 4 | 3.2 | No |
| 118135 |  CHEMBL387542 | C51H68N6O19 | 1069.13 | 20 / 17 | -3.3 | No |
| 118620 |  Senktide | C40H55N7O11S | 841.978 | 12 / 8 | 1.1 | No |
| 561039 |  CHEMBL2370702 | C38H50N8O7S | 762.927 | 8 / 8 | 2.2 | No |
| 446436 |  125989-12-0 | C38H50N8O7S | 762.927 | 8 / 8 | 2.2 | No |
| 121833 |  CHEMBL2370056 | C51H65N9O9 | 948.135 | 10 / 7 | 3.8 | No |
| 123243 |  CHEMBL435619 | C23H28FN3O | 381.495 | 4 / 3 | 3.2 | Yes |
| 125282 |  CHEMBL131872 | C42H68N10O11S | 921.125 | 14 / 11 | -3.1 | No |
| 127005 |  CHEMBL223993 | C39H48N6O9 | 744.846 | 10 / 11 | 0.4 | No |
| 127635 |  CHEMBL566468 | C21H19N | 285.39 | 1 / 0 | 4.5 | Yes |
| 128294 |  CHEMBL340405 | C23H25FN4O2 | 408.477 | 5 / 1 | 2.9 | Yes |
| 129127 |  GR100679 | C34H44N6O5 | 616.763 | 5 / 5 | 3.4 | No |
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