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| Name | C-C chemokine receptor type 2 |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ccr2 |
| Synonym | JE/FIC receptor CKR2 chemokine receptor CCR2 chemokine (C-C motif) receptor 2 CD192 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 373 |
| Amino acid sequence | MEDNNMLPQFIHGILSTSHSLFTRSIQELDEGATTPYDYDDGEPCHKTSVKQIGAWILPPLYSLVFIFGFVGNMLVIIILIGCKKLKSMTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVITSVVTWVVAVFASLPGIIFTKSKQDDHHYTCGPYFTQLWKNFQTIMRNILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLFLTTFQESLGMSNCVIDKHLDQAMQVTETLGMTHCCINPVIYAFVGEKFRRYLSIFFRKHIAKRLCKQCPVFYRETADRVSSTFTPSTGEQEVSVGL |
| UniProt | P51683 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5412 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 318 |  CHEMBL231340 | C37H35F6N5O2S | 727.77 | 12 / 2 | 7.2 | No |
| 463237 |  CHEMBL3588870 | C33H33F7N2O3 | 638.627 | 11 / 1 | 6.6 | No |
| 5929 |  CHEMBL1171006 | C20H12ClF4NO5S | 489.822 | 10 / 2 | 5.1 | No |
| 7115 |  CHEMBL388675 | C30H32F6N2OS | 582.649 | 9 / 1 | 7.5 | No |
| 34802 |  CHEMBL230933 | C31H36F4N2O | 528.636 | 6 / 1 | 7.3 | No |
| 34975 |  CHEMBL397647 | C21H25Cl2N2O2+ | 408.343 | 2 / 1 | 4.7 | Yes |
| 36966 |  CHEMBL230831 | C31H34F6N2O2 | 580.615 | 9 / 1 | 6.6 | No |
| 38334 |  CHEMBL231246 | C30H34F4N2OS | 546.669 | 7 / 1 | 6.6 | No |
| 39163 |  CHEMBL231142 | C33H38F4N2O | 554.674 | 6 / 1 | 8.0 | No |
| 43765 |  CHEMBL237967 | C29H30F3N3O3 | 525.572 | 7 / 2 | 2.6 | No |
| 53052 |  1269775-42-9 | C24H34ClN7O3 | 504.032 | 7 / 3 | N/A | No |
| 56372 |  CHEMBL1171208 | C19H13ClFNO5S | 421.823 | 7 / 2 | 4.2 | Yes |
| 61965 |  CHEMBL388869 | C37H34F6N4O2S | 712.755 | 11 / 2 | 8.3 | No |
| 66706 |  CHEMBL1683074 | C25H37F3N4O3 | 498.591 | 9 / 1 | 3.0 | Yes |
| 76234 |  CHEMBL388007 | C31H34F6N2O | 564.616 | 8 / 1 | 7.6 | No |
| 78325 |  CHEMBL1170391 | C20H12ClF4NO5S | 489.822 | 10 / 2 | 5.1 | No |
| 83428 |  CHEMBL231143 | C34H42F4N2O | 570.717 | 6 / 1 | 9.0 | No |
| 88756 |  CHEMBL230721 | C32H36F6N2O | 578.643 | 8 / 1 | 8.1 | No |
| 135784 |  CHEMBL1171758 | C19H14ClNO5S | 403.833 | 6 / 2 | 4.0 | Yes |
| 136760 |  CHEMBL387587 | C32H36F6N2O | 578.643 | 8 / 1 | 8.2 | No |
| 138656 |  CHEMBL388380 | C29H30F6N2O | 536.562 | 8 / 1 | 6.9 | No |
| 143609 |  CHEMBL1171586 | C20H13ClF3NO5S | 471.831 | 9 / 2 | 5.0 | Yes |
| 481068 |  CHEMBL3589950 | C32H33F5N2O3 | 588.619 | 9 / 1 | 5.8 | No |
| 161654 |  CHEMBL231150 | C39H38F6N4O2S | 740.809 | 11 / 2 | 8.8 | No |
| 163970 |  CHEMBL230078 | C33H36F6N2O | 590.654 | 8 / 1 | 8.2 | No |
| 178732 |  CHEMBL398000 | C33H38F6N2O | 592.67 | 8 / 1 | 8.4 | No |
| 183516 |  CHEMBL1169652 | C20H13ClN2O5S | 428.843 | 7 / 2 | 3.8 | Yes |
| 185756 |  CHEMBL1169653 | C19H13ClFNO5S | 421.823 | 7 / 2 | 4.2 | Yes |
| 486482 |  CHEMBL3589839 | C26H28F6N2O2 | 514.512 | 9 / 1 | 4.9 | No |
| 190791 |  CHEMBL230722 | C29H32F4N2O | 500.582 | 6 / 1 | 6.5 | No |
| 204245 |  CHEMBL1688889 | C24H33N7O3 | 467.574 | 7 / 2 | 3.5 | Yes |
| 205103 |  CHEMBL226065 | C29H30F6N2O | 536.562 | 8 / 1 | 6.9 | No |
| 205104 |  CHEMBL230616 | C29H30F6N2O | 536.562 | 8 / 1 | 6.9 | No |
| 205511 |  CHEMBL231247 | C29H32F4N2OS | 532.642 | 7 / 1 | 6.7 | No |
| 490064 |  CHEMBL3589840 | C27H30F6N2O2 | 528.539 | 9 / 1 | 5.3 | No |
| 222563 |  CHEMBL231039 | C32H38F4N2O | 542.663 | 6 / 1 | 7.7 | No |
| 222586 |  CHEMBL1171761 | C20H16ClNO5S | 417.86 | 6 / 2 | 4.5 | Yes |
| 223680 |  CHEMBL436796 | C32H36F4N2O | 540.647 | 6 / 1 | 7.4 | No |
| 235391 |  CHEMBL230405 | C34H38F6N2O | 604.681 | 8 / 1 | 8.8 | No |
| 246306 |  CHEMBL2036782 | C19H27Cl2N5O2 | 428.358 | 4 / 2 | 1.9 | Yes |
| 494095 |  CHEMBL3589949 | C32H33F5N2O2 | 572.62 | 8 / 1 | 6.3 | No |
| 255696 |  CHEMBL389610 | C30H34F4N2O2 | 530.608 | 7 / 1 | 5.8 | No |
| 494781 |  CHEMBL3589951 | C31H31F5N2O3 | 574.592 | 9 / 2 | 5.5 | No |
| 495754 |  CHEMBL3589847 | C31H31F5N2O2 | 558.593 | 8 / 1 | 5.9 | No |
| 266133 |  CHEMBL1171207 | C20H16ClNO5S | 417.86 | 6 / 2 | 4.5 | Yes |
| 270167 |  CHEMBL266017 | C32H34F6N2O | 576.627 | 8 / 1 | 7.9 | No |
| 272957 |  CHEMBL398001 | C35H42F6N2O | 620.724 | 8 / 1 | 9.8 | No |
| 497353 |  CHEMBL3589845 | C32H31F7N2O2 | 608.601 | 10 / 1 | 6.7 | No |
| 285844 |  CHEMBL230832 | C31H34F6N2OS | 596.676 | 9 / 1 | 7.4 | No |
| 288045 |  CHEMBL231038 | C31H36F4N2O | 528.636 | 6 / 1 | 7.4 | No |
| 288609 |  CHEMBL231149 | C36H33F6N5O2S | 713.743 | 12 / 2 | 7.2 | No |
| 299170 |  CHEMBL397717 | C39H36F6N4O2S | 738.793 | 11 / 2 | 7.8 | No |
| 307376 |  CHEMBL437359 | C31H34F4N2O | 526.62 | 6 / 1 | 7.1 | No |
| 315332 |  CHEMBL1171938 | C19H13Cl2NO5S | 438.275 | 6 / 2 | 4.8 | Yes |
| 322061 |  CHEMBL395289 | C36H34F6N4O2S2 | 732.804 | 12 / 2 | 7.9 | No |
| 331942 |  CHEMBL226066 | C30H32F6N2O | 550.589 | 8 / 1 | 7.3 | No |
| 331944 |  CHEMBL230617 | C30H32F6N2O | 550.589 | 8 / 1 | 7.3 | No |
| 338483 |  CHEMBL1171760 | C19H13Cl2NO5S | 438.275 | 6 / 2 | 4.8 | Yes |
| 505205 |  CHEMBL3589843 | C26H30F4N2O2 | 478.532 | 7 / 1 | 4.5 | Yes |
| 348342 |  CHEMBL438128 | C38H36F6N4O2S | 726.782 | 11 / 2 | 8.2 | No |
| 506426 |  CHEMBL3589842 | C25H28F4N2O2 | 464.505 | 7 / 1 | 4.1 | Yes |
| 506447 |  TAK-779 | C33H39ClN2O2 | 531.137 | 3 / 1 | N/A | No |
| 377107 |  CHEMBL2018386 | C28H38F3N5O4 | 565.638 | 8 / 6 | 3.8 | No |
| 509488 |  CHEMBL3589846 | C33H33F7N2O2 | 622.628 | 10 / 1 | 7.1 | No |
| 378457 |  CHEMBL1688888 | C17H13F4N5O2 | 395.318 | 8 / 2 | 3.2 | Yes |
| 510590 |  CHEMBL3589841 | C27H30F6N2O3 | 544.538 | 10 / 1 | 4.8 | No |
| 386430 |  CHEMBL230932 | C30H34F4N2O | 514.609 | 6 / 1 | 6.9 | No |
| 511762 |  CHEMBL3589844 | C26H30F4N2O3 | 494.531 | 8 / 1 | 4.0 | Yes |
| 519479 |  TAK779 | C33H39N2O2+ | 495.687 | 2 / 1 | 6.4 | No |
| 409938 |  CHEMBL2207081 | C15H11Cl3N4O2S | 417.689 | 5 / 1 | 3.7 | Yes |
| 513745 |  CHEMBL3589952 | C29H32F6N2O2 | 554.577 | 9 / 1 | 6.0 | No |
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