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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL230933
Molecular formula	C31H36F4N2O
IUPAC name	(1S,3R)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]-1-propan-2-ylcyclopentane-1-carboxamide
Molecular weight	528.636
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	7.3
Synonyms	(1S,3R)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-3-[(1S,5''R)-5''-methylspiro[indene-1,4''-piperidine]-1''-yl]-1-(propan-2-yl)cyclopentane-1-carboxamide BDBM50212136
Inchi Key	BWWUOZUJVUFGJV-KAXVLVORSA-N
Inchi ID	InChI=1S/C31H36F4N2O/c1-20(2)30(28(38)36-18-22-14-24(31(33,34)35)16-25(32)15-22)11-9-26(17-30)37-13-12-29(21(3)19-37)10-8-23-6-4-5-7-27(23)29/h4-8,10,14-16,20-21,26H,9,11-13,17-19H2,1-3H3,(H,36,38)/t21-,26+,29+,30-/m0/s1
PubChem CID	44425645
ChEMBL	CHEMBL230933
IUPHAR	N/A
BindingDB	50212136
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34801	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
34802	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373

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