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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL388380
Molecular formula	C29H30F6N2O
IUPAC name	(1S,3R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-methyl-3-spiro[indene-1,4'-piperidine]-1'-ylcyclopentane-1-carboxamide
Molecular weight	536.562
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	6.9
Synonyms	BDBM50211500 (1S,3R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-1-methyl-3-{spiro[indene-1,4''-piperidine]-1''-yl}cyclopentane-1-carboxamide
Inchi Key	IPKKUXDCFVLCMQ-BVAGGSTKSA-N
Inchi ID	InChI=1S/C29H30F6N2O/c1-26(25(38)36-18-19-14-21(28(30,31)32)16-22(15-19)29(33,34)35)8-7-23(17-26)37-12-10-27(11-13-37)9-6-20-4-2-3-5-24(20)27/h2-6,9,14-16,23H,7-8,10-13,17-18H2,1H3,(H,36,38)/t23-,26+/m1/s1
PubChem CID	44423285
ChEMBL	CHEMBL388380
IUPHAR	N/A
BindingDB	50211500
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
138655	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
138656	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373

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