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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3589845
Molecular formula	C32H31F7N2O2
IUPAC name	N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluorophenyl)-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Molecular weight	608.601
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	6.7
Synonyms	BDBM50097887 N-[3,5-Bis(trifluoromethyl)benzyl]-2-(4-fluorophenyl)-4-(3,4-dihydrospiro[1H-2-benzopyran-1,4'-piperidine]-1'-yl)butanamide
Inchi Key	QHHGOEMDEWUDCB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H31F7N2O2/c33-26-7-5-22(6-8-26)27(29(42)40-20-21-17-24(31(34,35)36)19-25(18-21)32(37,38)39)9-13-41-14-11-30(12-15-41)28-4-2-1-3-23(28)10-16-43-30/h1-8,17-19,27H,9-16,20H2,(H,40,42)
PubChem CID	122181150
ChEMBL	CHEMBL3589845
IUPHAR	N/A
BindingDB	50097887
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
497352	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
497353	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373

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