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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3589952
Molecular formula	C29H32F6N2O2
IUPAC name	N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-cyclopropyl-4-spiro[3,4-dihydroisochromene-1,4'-piperidine]-1'-ylbutanamide
Molecular weight	554.577
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	6.0
Synonyms	N-[3,5-Bis(trifluoromethyl)benzyl]-2-cyclopropyl-4-(3,4-dihydrospiro[1H-2-benzopyran-1,4'-piperidine]-1'-yl)butanamide BDBM50097901
Inchi Key	YKBMRTZYUFOORD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H32F6N2O2/c30-28(31,32)22-15-19(16-23(17-22)29(33,34)35)18-36-26(38)24(20-5-6-20)7-11-37-12-9-27(10-13-37)25-4-2-1-3-21(25)8-14-39-27/h1-4,15-17,20,24H,5-14,18H2,(H,36,38)
PubChem CID	122181238
ChEMBL	CHEMBL3589952
IUPHAR	N/A
BindingDB	50097901
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
513744	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
513745	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373

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