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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL389610
Molecular formula	C30H34F4N2O2
IUPAC name	N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-1-(methoxymethyl)-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamide
Molecular weight	530.608
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50212125 N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-1-(methoxymethyl)-3-[(1S,5''R)-5''-methylspiro[indene-1,4''-piperidine]-1''-yl]cyclopentane-1-carboxamide
Inchi Key	PBLHODZBJXXWDD-FYZPOUGESA-N
Inchi ID	InChI=1S/C30H34F4N2O2/c1-20-18-36(12-11-29(20)10-7-22-5-3-4-6-26(22)29)25-8-9-28(16-25,19-38-2)27(37)35-17-21-13-23(30(32,33)34)15-24(31)14-21/h3-7,10,13-15,20,25H,8-9,11-12,16-19H2,1-2H3,(H,35,37)/t20-,25?,28?,29+/m0/s1
PubChem CID	44425651
ChEMBL	CHEMBL389610
IUPHAR	N/A
BindingDB	50212125
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
255695	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
255696	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373

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