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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL436796
Molecular formula	C32H36F4N2O
IUPAC name	1-(cyclopropylmethyl)-N-[[3-fluoro-5-(trifluoromethyl)phenyl]methyl]-3-[(1S,3'R)-3'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamide
Molecular weight	540.647
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	7.4
Synonyms	BDBM50212131 1-(cyclopropylmethyl)-N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-3-[(1S,5''R)-5''-methylspiro[indene-1,4''-piperidine]-1''-yl]cyclopentane-1-carboxamide
Inchi Key	NHWLZHAUUGGYKT-SKDYKVSPSA-N
Inchi ID	InChI=1S/C32H36F4N2O/c1-21-20-38(13-12-31(21)11-8-24-4-2-3-5-28(24)31)27-9-10-30(18-27,17-22-6-7-22)29(39)37-19-23-14-25(32(34,35)36)16-26(33)15-23/h2-5,8,11,14-16,21-22,27H,6-7,9-10,12-13,17-20H2,1H3,(H,37,39)/t21-,27?,30?,31+/m0/s1
PubChem CID	44425648
ChEMBL	CHEMBL436796
IUPHAR	N/A
BindingDB	50212131
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
223680	C-C chemokine receptor type 2	P51683	Ccr2	Mus musculus (Mouse)	373
223681	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374

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