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Name | G-protein coupled receptor 4 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR4 |
Synonym | G-protein coupled receptor 19 GPR19 GPR4 |
Disease | N/A |
Length | 362 |
Amino acid sequence | MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPPAQ |
UniProt | P46093 |
Protein Data Bank | N/A |
GPCR-HGmod model | P46093 |
3D structure model | This predicted structure model is from GPCR-EXP P46093. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3638324 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
1605 | CHEMBL3675725 | C28H38N6O2 | 490.652 | 6 / 2 | 2.6 | Yes |
521493 | CHEMBL3810032 | C25H26N4 | 382.511 | 3 / 1 | 5.7 | No |
521626 | CHEMBL3810295 | C27H22N2 | 374.487 | 1 / 1 | 6.8 | No |
521663 | CHEMBL3810132 | C23H20N2 | 324.427 | 1 / 1 | 5.4 | No |
11143 | CHEMBL3670936 | C33H45N5O4 | 575.754 | 6 / 1 | 4.9 | No |
11667 | CHEMBL3670930 | C29H38N4O3 | 490.648 | 5 / 1 | 4.9 | Yes |
12167 | CHEMBL3675739 | C26H33N7 | 443.599 | 5 / 1 | 3.3 | Yes |
13240 | CHEMBL3675736 | C25H35N5O2 | 437.588 | 6 / 1 | 3.2 | Yes |
521900 | CHEMBL3809759 | C20H21N3 | 303.409 | 2 / 1 | 4.3 | Yes |
16193 | CHEMBL3670938 | C25H33N5 | 403.574 | 4 / 1 | 4.1 | Yes |
521959 | SCHEMBL5426008 | C24H23N3O | 369.468 | 3 / 0 | 5.2 | No |
522355 | CHEMBL3728144 | C28H26N4O | 434.543 | 3 / 1 | 6.0 | No |
28369 | CHEMBL3670937 | C25H33N5O | 419.573 | 5 / 2 | 3.1 | Yes |
37728 | CHEMBL3670932 | C25H32N4O | 404.558 | 4 / 2 | 4.0 | Yes |
42361 | CHEMBL3675741 | C24H30N8 | 430.56 | 6 / 1 | 2.5 | Yes |
51095 | CHEMBL3675726 | C29H38N6O2 | 502.663 | 6 / 2 | 3.3 | No |
58506 | CHEMBL3639746 | C27H39N5 | 433.644 | 4 / 0 | 5.1 | No |
70568 | CHEMBL3675724 | C24H31N5 | 389.547 | 4 / 1 | 3.7 | Yes |
524561 | SCHEMBL5417472 | C23H31N5 | 377.536 | 4 / 2 | 4.2 | Yes |
105355 | CHEMBL3675730 | C23H30N4O | 378.52 | 4 / 1 | 4.2 | Yes |
126538 | CHEMBL3675743 | C24H28N6O | 416.529 | 6 / 1 | 3.5 | Yes |
131447 | CHEMBL3670931 | C28H36N4O3 | 476.621 | 5 / 1 | 4.6 | Yes |
525457 | SCHEMBL9129857 | C22H28N4O2 | 380.492 | 4 / 1 | 4.5 | Yes |
525483 | CHEMBL3809413 | C31H38N6 | 494.687 | 5 / 1 | 5.4 | No |
525623 | CHEMBL3810150 | C22H19N3 | 325.415 | 2 / 1 | 4.9 | Yes |
525668 | CHEMBL3809249 | C24H23N3 | 353.469 | 2 / 1 | 5.7 | No |
144334 | CHEMBL3675738 | C24H29N7 | 415.545 | 5 / 1 | 2.6 | Yes |
155577 | CHEMBL3670933 | C30H42N4O3 | 506.691 | 5 / 1 | 5.4 | No |
168715 | CHEMBL3675742 | C30H39N7O3 | 545.688 | 7 / 1 | 4.2 | No |
169982 | CHEMBL3670942 | C28H40N6 | 460.67 | 5 / 0 | 4.3 | Yes |
185565 | CHEMBL3675728 | C25H31N5O | 417.557 | 4 / 0 | 3.6 | Yes |
198887 | CHEMBL3670934 | C26H34N4O | 418.585 | 4 / 2 | 4.5 | Yes |
527371 | CHEMBL3727521 | C23H24N4 | 356.473 | 3 / 1 | 5.4 | No |
527547 | SCHEMBL6046517 | C30H35N5O | 481.644 | 5 / 1 | 5.2 | No |
221266 | CHEMBL3675734 | C24H32N4O2 | 408.546 | 5 / 2 | 3.5 | Yes |
527981 | CHEMBL3808576 | C23H22N4S | 386.517 | 4 / 1 | 5.6 | No |
528111 | SCHEMBL5780505 | C23H24N4 | 356.473 | 3 / 1 | 5.4 | No |
528234 | CHEMBL3731852 | C29H33N5O | 467.617 | 5 / 1 | 5.8 | No |
528255 | CHEMBL3810343 | C21H21N3 | 315.42 | 2 / 0 | 5.1 | No |
528621 | CHEMBL3810339 | C17H19N3 | 265.36 | 2 / 0 | 3.9 | Yes |
252203 | CHEMBL3675731 | C28H37N5O3 | 491.636 | 6 / 2 | 3.8 | Yes |
255698 | CHEMBL3670940 | C26H34N6O | 446.599 | 5 / 1 | 2.7 | Yes |
528892 | CHEMBL3808954 | C19H19N3 | 289.382 | 2 / 1 | 3.8 | Yes |
529320 | CHEMBL3809977 | C25H24N4 | 380.495 | 3 / 1 | 5.9 | No |
530647 | SCHEMBL5428753 | C27H37N5O | 447.627 | 5 / 1 | 4.6 | Yes |
325980 | CHEMBL3675737 | C24H28N6O | 416.529 | 5 / 1 | 2.8 | Yes |
332008 | GPR4 antagonist 1 | C27H37N5 | 431.628 | 4 / 0 | 5.0 | Yes |
530925 | CHEMBL3808552 | C18H17N3 | 275.355 | 2 / 1 | 3.4 | Yes |
340768 | CHEMBL3670935 | C28H38N4O3 | 478.637 | 6 / 3 | 3.2 | Yes |
343424 | CHEMBL3670939 | C26H35N5O | 433.6 | 5 / 1 | 3.6 | Yes |
531256 | CHEMBL3808563 | C23H21N3 | 339.442 | 2 / 1 | 5.3 | No |
355648 | CHEMBL3675740 | C25H31N7 | 429.572 | 5 / 1 | 3.0 | Yes |
363805 | CHEMBL3670941 | C27H34N8 | 470.625 | 6 / 0 | 4.3 | Yes |
531778 | SCHEMBL6046468 | C30H35N5 | 465.645 | 4 / 1 | 6.1 | No |
369845 | CHEMBL3675727 | C33H51N5O2Si | 577.889 | 6 / 1 | N/A | No |
391336 | CHEMBL3675735 | C28H39N5O3 | 493.652 | 6 / 0 | 4.5 | Yes |
533083 | CHEMBL3810385 | C31H37N5 | 479.672 | 4 / 1 | 6.4 | No |
429257 | CHEMBL3675729 | C29H39N5O3 | 505.663 | 5 / 0 | 4.2 | No |
438272 | CHEMBL3675745 | C28H35N7O3 | 517.634 | 8 / 2 | 2.4 | No |
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