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GPCR

NameG-protein coupled receptor 4
SpeciesHomo sapiens (Human)
GeneGPR4
SynonymG-protein coupled receptor 19
GPR19
GPR4
DiseaseN/A
Length362
Amino acid sequenceMGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPPAQ
UniProtP46093
Protein Data BankN/A
GPCR-HGmod modelP46093
3D structure modelThis predicted structure model is from GPCR-EXP P46093.
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3638324
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 59
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
16052D structureCHEMBL3675725C28H38N6O2490.6526 / 22.6Yes
5214932D structureCHEMBL3810032C25H26N4382.5113 / 15.7No
5216262D structureCHEMBL3810295C27H22N2374.4871 / 16.8No
5216632D structureCHEMBL3810132C23H20N2324.4271 / 15.4No
111432D structureCHEMBL3670936C33H45N5O4575.7546 / 14.9No
116672D structureCHEMBL3670930C29H38N4O3490.6485 / 14.9Yes
121672D structureCHEMBL3675739C26H33N7443.5995 / 13.3Yes
132402D structureCHEMBL3675736C25H35N5O2437.5886 / 13.2Yes
5219002D structureCHEMBL3809759C20H21N3303.4092 / 14.3Yes
161932D structureCHEMBL3670938C25H33N5403.5744 / 14.1Yes
5219592D structureSCHEMBL5426008C24H23N3O369.4683 / 05.2No
5223552D structureCHEMBL3728144C28H26N4O434.5433 / 16.0No
283692D structureCHEMBL3670937C25H33N5O419.5735 / 23.1Yes
377282D structureCHEMBL3670932C25H32N4O404.5584 / 24.0Yes
423612D structureCHEMBL3675741C24H30N8430.566 / 12.5Yes
510952D structureCHEMBL3675726C29H38N6O2502.6636 / 23.3No
585062D structureCHEMBL3639746C27H39N5433.6444 / 05.1No
705682D structureCHEMBL3675724C24H31N5389.5474 / 13.7Yes
5245612D structureSCHEMBL5417472C23H31N5377.5364 / 24.2Yes
1053552D structureCHEMBL3675730C23H30N4O378.524 / 14.2Yes
1265382D structureCHEMBL3675743C24H28N6O416.5296 / 13.5Yes
1314472D structureCHEMBL3670931C28H36N4O3476.6215 / 14.6Yes
5254572D structureSCHEMBL9129857C22H28N4O2380.4924 / 14.5Yes
5254832D structureCHEMBL3809413C31H38N6494.6875 / 15.4No
5256232D structureCHEMBL3810150C22H19N3325.4152 / 14.9Yes
5256682D structureCHEMBL3809249C24H23N3353.4692 / 15.7No
1443342D structureCHEMBL3675738C24H29N7415.5455 / 12.6Yes
1555772D structureCHEMBL3670933C30H42N4O3506.6915 / 15.4No
1687152D structureCHEMBL3675742C30H39N7O3545.6887 / 14.2No
1699822D structureCHEMBL3670942C28H40N6460.675 / 04.3Yes
1855652D structureCHEMBL3675728C25H31N5O417.5574 / 03.6Yes
1988872D structureCHEMBL3670934C26H34N4O418.5854 / 24.5Yes
5273712D structureCHEMBL3727521C23H24N4356.4733 / 15.4No
5275472D structureSCHEMBL6046517C30H35N5O481.6445 / 15.2No
2212662D structureCHEMBL3675734C24H32N4O2408.5465 / 23.5Yes
5279812D structureCHEMBL3808576C23H22N4S386.5174 / 15.6No
5281112D structureSCHEMBL5780505C23H24N4356.4733 / 15.4No
5282342D structureCHEMBL3731852C29H33N5O467.6175 / 15.8No
5282552D structureCHEMBL3810343C21H21N3315.422 / 05.1No
5286212D structureCHEMBL3810339C17H19N3265.362 / 03.9Yes
2522032D structureCHEMBL3675731C28H37N5O3491.6366 / 23.8Yes
2556982D structureCHEMBL3670940C26H34N6O446.5995 / 12.7Yes
5288922D structureCHEMBL3808954C19H19N3289.3822 / 13.8Yes
5293202D structureCHEMBL3809977C25H24N4380.4953 / 15.9No
5306472D structureSCHEMBL5428753C27H37N5O447.6275 / 14.6Yes
3259802D structureCHEMBL3675737C24H28N6O416.5295 / 12.8Yes
3320082D structureGPR4 antagonist 1C27H37N5431.6284 / 05.0Yes
5309252D structureCHEMBL3808552C18H17N3275.3552 / 13.4Yes
3407682D structureCHEMBL3670935C28H38N4O3478.6376 / 33.2Yes
3434242D structureCHEMBL3670939C26H35N5O433.65 / 13.6Yes
5312562D structureCHEMBL3808563C23H21N3339.4422 / 15.3No
3556482D structureCHEMBL3675740C25H31N7429.5725 / 13.0Yes
3638052D structureCHEMBL3670941C27H34N8470.6256 / 04.3Yes
5317782D structureSCHEMBL6046468C30H35N5465.6454 / 16.1No
3698452D structureCHEMBL3675727C33H51N5O2Si577.8896 / 1N/ANo
3913362D structureCHEMBL3675735C28H39N5O3493.6526 / 04.5Yes
5330832D structureCHEMBL3810385C31H37N5479.6724 / 16.4No
4292572D structureCHEMBL3675729C29H39N5O3505.6635 / 04.2No
4382722D structureCHEMBL3675745C28H35N7O3517.6348 / 22.4No

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