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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3675727
Molecular formula	C33H51N5O2Si
IUPAC name	(2R)-1-[tert-butyl(dimethyl)silyl]oxy-3-[4-[(E)-3-[4-[(2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl]phenyl]prop-2-enyl]piperazin-1-yl]propan-2-ol
Molecular weight	577.889
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	None
Synonyms	BDBM123492 US8748435, 17
Inchi Key	WCFXFXUDOPZAGD-WBKPCLEFSA-N
Inchi ID	InChI=1S/C33H51N5O2Si/c1-9-31-30(32-34-25(2)21-26(3)38(32)35-31)22-28-14-12-27(13-15-28)11-10-16-36-17-19-37(20-18-36)23-29(39)24-40-41(7,8)33(4,5)6/h10-15,21,29,39H,9,16-20,22-24H2,1-8H3/b11-10+/t29-/m1/s1
PubChem CID	86766088
ChEMBL	CHEMBL3675727
IUPHAR	N/A
BindingDB	123492
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
369845	G-protein coupled receptor 4	P46093	GPR4	Homo sapiens (Human)	362

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