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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Volinanserin
Molecular formula	C22H28FNO3
IUPAC name	(R)-(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
Molecular weight	373.468
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.9
Synonyms	(R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL API0000883 D0S6PV HXTGXYRHXAGCFP-OAQYLSRUSA-N MDL-100,907 NCGC00254173-01 Volinanserin [INN] (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (R)-(2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol AC1NSKC8 CAS-139290-65-6 DSSTox_RID_82298 M-100907 MDL-100907(Volinanserin) SCHEMBL675164 (R)-(+)-?-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol AKOS022180892 CS-0003646 FT-0675845 Mdl 100,907 MolPort-003-850-862 UNII-EW71EE171J (R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol 4-Piperidinemethanol, alpha-(2,3-dimethoxyphenyl)-1-(2-(4-fluorophenyl)ethyl)-, (+)- AS-35103 DSSTox_CID_27363 HY-14940 MDL-100.907 PB23201 Volinanserin; MDL 100907, (R)-(+)- (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907) (R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol AJ-23647 DTXSID6047363 M100907 MDL100.907 Serotonin 5-HT2 Receptor Antagonists (R)-(+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol 139290-65-6 alpha-(2,3-Dimethoxyphenyl)-1-(2-(4-fluorophenylethyl))-4-piperidine methanol D0HZ2E GTPL185 Mdl 100907 NCGC00247964-01 (R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol BDBM50095027 DSSTox_GSID_47363 KS-000007QR MDL-100907 Q-3721 ZINC598040 (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907) (R)-(2,3-dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol AK-59012 CHEMBL74355 EW71EE171J M100907, >=98% (HPLC) MDL100907 Tox21_300244 [ Show all ]
Inchi Key	HXTGXYRHXAGCFP-OAQYLSRUSA-N
Inchi ID	InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3/t21-/m1/s1
PubChem CID	5311271
ChEMBL	CHEMBL74355
IUPHAR	185
BindingDB	50095027
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126640	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
126637	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
126638	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
126643	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
126641	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
126644	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
126639	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
126646	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
126647	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
126645	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
126642	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
555982	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
555983	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
126636	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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