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| Name | G-protein coupled receptor 183 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | GPR183 |
| Synonym | EBI2 {ECO:0000303|PubMed:8383238} lymphocyte-specific G protein-coupled receptor hEBI2 {ECO:0000303|PubMed:22875855} GPR183 G protein-coupled receptor 183 [ Show all ] |
| Disease | N/A |
| Length | 361 |
| Amino acid sequence | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK |
| UniProt | P32249 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P32249 |
| 3D structure model | This predicted structure model is from GPCR-EXP P32249. |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3259470 |
| IUPHAR | 81 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 463429 |  CHEMBL3561833 | C22H25FN2O3S | 416.511 | 5 / 0 | 3.9 | Yes |
| 463557 |  AC1MADJ6 | C22H25FN2O3S | 416.511 | 5 / 0 | 3.7 | Yes |
| 463916 |  CHEMBL3560573 | C20H19BrF2N2O | 421.286 | 4 / 0 | 4.0 | Yes |
| 464225 |  AC1MAF8U | C19H18F2N2O3S | 392.421 | 6 / 0 | 2.6 | Yes |
| 13986 |  CHEMBL3262881 | C22H24N2O3 | 364.445 | 3 / 0 | 2.6 | Yes |
| 464782 |  CHEMBL3561756 | C21H22BrFN2O | 417.322 | 3 / 0 | 4.3 | Yes |
| 464798 |  CHEMBL3560763 | C19H18ClFN2O3S | 408.872 | 5 / 0 | 3.2 | Yes |
| 466100 |  AC1MAX4J | C19H18F2N2O3S | 392.421 | 6 / 0 | 2.6 | Yes |
| 29883 |  CHEMBL3262876 | C24H24N2O3 | 388.467 | 3 / 0 | 3.5 | Yes |
| 553408 |  7beta, 25-dihydroxycholesterol | C27H46O3 | 418.662 | 3 / 3 | 5.7 | No |
| 553409 |  7alpha,25-Dihydroxycholesterol | C27H46O3 | 418.662 | 3 / 3 | 5.7 | No |
| 466888 |  CHEMBL3559855 | C20H19Cl3N2O | 409.735 | 2 / 0 | 5.0 | Yes |
| 467867 |  CHEMBL3559978 | C20H21BrN2O3S | 449.363 | 4 / 0 | 3.5 | Yes |
| 468768 |  CHEMBL3559986 | C22H25BrN2O | 413.359 | 2 / 0 | 4.5 | Yes |
| 468778 |  CHEMBL3561798 | C17H23BrN2O | 351.288 | 2 / 0 | 3.6 | Yes |
| 469333 |  AC1OX4NE | C20H18FN3O3S | 399.44 | 6 / 0 | 2.2 | Yes |
| 469340 |  CHEMBL3559896 | C19H17Br2FN2O3S | 532.222 | 5 / 0 | 3.9 | No |
| 469428 |  AC1LI68F | C15H19BrN2O | 323.234 | 2 / 0 | 2.7 | Yes |
| 469899 |  CHEMBL3560864 | C20H19BrN2O2 | 399.288 | 2 / 0 | 3.4 | Yes |
| 470301 |  AC1MARAZ | C19H19FN2O3S | 374.43 | 5 / 0 | 2.5 | Yes |
| 472117 |  AC1MB8CK | C20H21FN2O4S | 404.456 | 6 / 0 | 2.5 | Yes |
| 553705 |  27-hydroxycholesterol | C27H46O2 | 402.663 | 2 / 2 | 7.1 | No |
| 91573 |  CHEMBL3262890 | C23H24N2O5 | 408.454 | 5 / 0 | 2.6 | Yes |
| 474261 |  CHEMBL3561495 | C21H19BrClF3N2O | 487.745 | 5 / 0 | 5.3 | No |
| 474354 |  CHEMBL3561862 | C18H16BrClN2O2 | 407.692 | 2 / 0 | 3.6 | Yes |
| 475817 |  CHEMBL3560209 | C23H26Cl2N2O3S | 481.432 | 4 / 0 | 5.4 | No |
| 476173 |  AC1LOGL1 | C20H21BrN2O | 385.305 | 2 / 0 | 3.8 | Yes |
| 477803 |  CHEMBL3560897 | C20H20BrFN2O | 403.295 | 3 / 0 | 3.9 | Yes |
| 477824 |  AC1PI39M | C17H17FN2O3S2 | 380.452 | 6 / 0 | 2.5 | Yes |
| 477853 |  CHEMBL3560750 | C19H18BrFN2O3S | 453.326 | 5 / 0 | 3.2 | Yes |
| 130153 |  CHEMBL3262893 | C23H26N2O3 | 378.472 | 3 / 0 | 3.4 | Yes |
| 479401 |  CHEMBL3560195 | C20H20BBrN2O4 | 443.104 | 4 / 2 | N/A | N/A |
| 134451 |  CHEMBL3262885 | C22H21F3N2O3 | 418.416 | 6 / 0 | 3.6 | Yes |
| 553974 |  25-Hydroxycholesterol | C27H46O2 | 402.663 | 2 / 2 | 6.8 | No |
| 481115 |  CHEMBL3560431 | C19H18FN3O5S | 419.427 | 7 / 0 | 2.4 | Yes |
| 481310 |  CHEMBL3561045 | C21H22BrClN2O2 | 449.773 | 2 / 0 | 4.2 | Yes |
| 481594 |  CHEMBL3561595 | C19H18ClFN2O3S | 408.872 | 5 / 0 | 3.2 | Yes |
| 481634 |  CHEMBL3561698 | C19H17Cl2FN2O3S | 443.314 | 5 / 0 | 3.8 | Yes |
| 482765 |  CHEMBL3560732 | C21H18BrF3N2O2 | 467.286 | 5 / 0 | 4.3 | Yes |
| 483221 |  AC1ORG3Z | C19H18F2N2O3S | 392.421 | 6 / 0 | 2.6 | Yes |
| 483395 |  CHEMBL3561084 | C20H21BrN2O4S | 465.362 | 5 / 0 | 3.1 | Yes |
| 174331 |  CHEMBL3262891 | C23H24N2O4 | 392.455 | 4 / 0 | 2.7 | Yes |
| 487911 |  CHEMBL3560404 | C23H27FN2O3S | 430.538 | 5 / 0 | 4.2 | Yes |
| 488224 |  CHEMBL3561739 | C21H19BrF4N2O | 471.294 | 6 / 0 | 4.8 | Yes |
| 209963 |  CHEMBL3262895 | C22H21BrN2O3 | 441.325 | 3 / 0 | 3.4 | Yes |
| 489343 |  CHEMBL3561800 | C21H23ClN2O3 | 386.876 | 4 / 1 | N/A | N/A |
| 489658 |  AC1P5TC7 | C21H23FN2O3S | 402.484 | 5 / 0 | 2.8 | Yes |
| 222682 |  CHEMBL3262883 | C22H23FN2O2 | 366.436 | 3 / 0 | 3.1 | Yes |
| 491198 |  1-[(4-fluorophenyl)sulfonyl]-4-[(2E)-3-phenylprop-2-enoyl]piperazine | C19H19FN2O3S | 374.43 | 5 / 0 | 2.5 | Yes |
| 492042 |  CHEMBL3560331 | C20H20BrClN2O | 419.747 | 2 / 0 | 4.4 | Yes |
| 492243 |  AC1MBBM0 | C23H21FN2O3S | 424.49 | 5 / 0 | 3.8 | Yes |
| 492508 |  CHEMBL3560082 | C20H21FN2O3S | 388.457 | 5 / 0 | 2.5 | Yes |
| 492674 |  CHEMBL3560453 | C21H18BrN3O2 | 424.298 | 3 / 0 | 3.1 | Yes |
| 239822 |  NIBR189 | C21H21BrN2O3 | 429.314 | 3 / 0 | 3.4 | Yes |
| 493955 |  CHEMBL3561208 | C18H23BrN2O2 | 379.298 | 2 / 0 | 3.1 | Yes |
| 494072 |  CHEMBL3559757 | C24H29BrN2O | 441.413 | 2 / 0 | 5.5 | No |
| 554523 |  7beta-Hydroxycholesterol | C27H46O2 | 402.663 | 2 / 2 | 7.4 | No |
| 554524 |  7alpha-Hydroxycholesterol | C27H46O2 | 402.663 | 2 / 2 | 7.4 | No |
| 253907 |  CHEMBL3262878 | C22H26N2O3 | 366.461 | 3 / 0 | 3.0 | Yes |
| 494431 |  CHEMBL3560888 | C21H21BrN2O2 | 413.315 | 2 / 0 | 3.8 | Yes |
| 494658 |  CHEMBL3561867 | C20H18BrF3N2O3S | 503.334 | 7 / 0 | 4.0 | No |
| 497833 |  CHEMBL3560117 | C23H23FN2O3S | 426.506 | 5 / 0 | 3.3 | Yes |
| 497942 |  AC1MBC9K | C21H21FN2O3S | 400.468 | 5 / 0 | 3.0 | Yes |
| 498559 |  CHEMBL3560513 | C19H20BrClN2O | 407.736 | 2 / 0 | 3.9 | Yes |
| 498728 |  CHEMBL3560820 | C21H23FN2O3S | 402.484 | 5 / 0 | 2.9 | Yes |
| 498840 |  CHEMBL3561364 | C20H17Cl3N2O2 | 423.718 | 2 / 0 | 4.6 | Yes |
| 293234 |  CHEMBL3262880 | C22H24N2O2 | 348.446 | 2 / 0 | 3.0 | Yes |
| 499522 |  CHEMBL3561484 | C20H19BrClFN2O | 437.737 | 3 / 0 | 4.5 | Yes |
| 500561 |  CHEMBL3560809 | C20H18BrClN2O2 | 433.73 | 2 / 0 | 4.1 | Yes |
| 500626 |  CHEMBL3561130 | C19H18BrFN2O3S | 453.326 | 5 / 0 | 3.2 | Yes |
| 500890 |  CHEMBL3560464 | C17H23BrN2O | 351.288 | 2 / 0 | 3.6 | Yes |
| 554780 |  7beta,26-dihydroxycholesterol | C27H46O3 | 418.662 | 3 / 3 | 6.0 | No |
| 554781 |  7alpha, 27-OHC | C27H46O3 | 418.662 | 3 / 3 | 6.0 | No |
| 312813 |  CHEMBL3262886 | C21H21BrN2O3 | 429.314 | 3 / 0 | 3.4 | Yes |
| 501854 |  CHEMBL3561255 | C21H23BrN2O | 399.332 | 2 / 0 | 4.2 | Yes |
| 323347 |  CHEMBL3262892 | C22H23ClN2O3 | 398.887 | 3 / 0 | 3.7 | Yes |
| 504253 |  CHEMBL3560411 | C22H26BrClN2O3 | 481.815 | 4 / 1 | N/A | N/A |
| 504350 |  CHEMBL3561875 | C18H18BrClN2O | 393.709 | 2 / 0 | 4.0 | Yes |
| 504656 |  CHEMBL3560529 | C19H18BrFN2O3S | 453.326 | 5 / 0 | 3.2 | Yes |
| 345120 |  CHEMBL3262884 | C22H24N2O3 | 364.445 | 3 / 0 | 3.1 | Yes |
| 505839 |  CHEMBL3560274 | C20H20BrFN2O | 403.295 | 3 / 0 | 3.9 | Yes |
| 506052 |  CHEMBL3561719 | C23H27BrN2O | 427.386 | 2 / 0 | 4.9 | Yes |
| 351165 |  CHEMBL3262877 | C20H21BrN2O3 | 417.303 | 3 / 0 | 3.0 | Yes |
| 352418 |  CHEMBL3262888 | C22H24N2O4 | 380.444 | 4 / 0 | 2.7 | Yes |
| 506675 |  CHEMBL3561230 | C20H21FN2O4S | 404.456 | 6 / 0 | 2.5 | Yes |
| 506737 |  CHEMBL3560041 | C20H19BrCl2N2O | 454.189 | 2 / 0 | 5.1 | No |
| 508663 |  AC1MAR9H | C20H21FN2O3S | 388.457 | 5 / 0 | 2.9 | Yes |
| 371069 |  CHEMBL3262882 | C21H20Cl2N2O2 | 403.303 | 2 / 0 | 3.9 | Yes |
| 371434 |  CHEMBL3262879 | C21H21BrN2O2 | 413.315 | 2 / 0 | 3.4 | Yes |
| 508853 |  CHEMBL3561444 | C21H23BrN2O4S | 479.389 | 5 / 0 | 3.5 | Yes |
| 509842 |  CHEMBL3559902 | C23H21FN2O3S | 424.49 | 5 / 0 | 3.8 | Yes |
| 510846 |  CHEMBL3561399 | C19H18Br2N2O3S | 514.232 | 4 / 0 | 3.8 | No |
| 511977 |  CHEMBL3561640 | C21H23FN2O3 | 370.424 | 5 / 1 | N/A | N/A |
| 399615 |  CHEMBL3262894 | C22H21ClN2O3 | 396.871 | 3 / 0 | 3.4 | Yes |
| 401524 |  CHEMBL1305842 | C20H21ClN2O3 | 372.849 | 3 / 0 | 2.9 | Yes |
| 413724 |  CHEMBL3262889 | C23H27N3O3 | 393.487 | 4 / 0 | 2.8 | Yes |
| 514419 |  AC1MARBE | C19H18ClFN2O3S | 408.872 | 5 / 0 | 3.2 | Yes |
| 514630 |  CHEMBL3560891 | C19H17Br2FN2O3S | 532.222 | 5 / 0 | 3.9 | No |
| 515660 |  CHEMBL3561859 | C19H18BrFN2O3S | 453.326 | 5 / 0 | 3.2 | Yes |
| 515785 |  CHEMBL3560415 | C22H25BrN2O3 | 445.357 | 4 / 0 | 3.7 | Yes |
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