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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-[(4-fluorophenyl)sulfonyl]-4-[(2E)-3-phenylprop-2-enoyl]piperazine
Molecular formula	C19H19FN2O3S
IUPAC name	(E)-1-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-3-phenylprop-2-en-1-one
Molecular weight	374.43
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.5
Synonyms	HMS1648O13 MolPort-006-054-547 SR-01000594830-1 HMS2707I14 AC1O2R1T SMR000315085 CHEMBL1557734 ZINC2939286 (E)-1-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]-3-phenylprop-2-en-1-one MLS000673844 AKOS002132201 SR-01000594830 [ Show all ]
Inchi Key	NNXVAJWZJWSQHU-IZZDOVSWSA-N
Inchi ID	InChI=1S/C19H19FN2O3S/c20-17-7-9-18(10-8-17)26(24,25)22-14-12-21(13-15-22)19(23)11-6-16-4-2-1-3-5-16/h1-11H,12-15H2/b11-6+
PubChem CID	6258671
ChEMBL	CHEMBL1557734
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
491198	G-protein coupled receptor 183	P32249	GPR183	Homo sapiens (Human)	361

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