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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	25-Hydroxycholesterol
Molecular formula	C27H46O2
IUPAC name	(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Molecular weight	402.663
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	6.8
Synonyms	Cholest-5-ene-3?,25-diol DSSTox_RID_80099 MolPort-006-169-893 140H467 Bicyclo[4.1.0]heptane-3,4-diol,3,7,7-trimethyl-, (1S,3S,4S,6R)- CTK4E6668 HC3 Tox21_112790 (3?)-Cholest-5-ene-3,25-diol 25-hydroxy-cholesterol 767JTD2N31 CAS-2140-46-7 cholest-5-en-3beta,25-diol DSSTox_CID_24023 LMST01010018 ZINC5751264 (3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-5-hydroxy-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 25-Hydroxycholesterol, >=98% AN-50434 Cholest-5-ene-3beta,25-diol DTXSID5044023 NCGC00181327-01 2140-46-7 5-cholesten-3beta,25-diol C-46012 CHEBI:42977 D06OVX HY-113134 UNII-767JTD2N31 (3BETA)-CHOLEST-5-ENE-3,25-DIOL 25-Hydroxycholest-5-en-3-ol AC1L22KV Cholest-5-ene-3,25-diol, (3b)- DSSTox_GSID_44023 MFCD00057815 (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol 25-OHC BDBM20182 CS-0061533 GTPL2885 SCHEMBL177267 (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0;{2,7}.0;{11,15}]heptadec-7-en-5-ol 25-hydroxy cholesterol 5-Cholestene-3beta,25-diol C15519 CHEMBL169046 DB04705 INBGSXNNRGWLJU-ZHHJOTBYSA-N W-201876 (3S,8S,9S,10R,13R,14S,17R)-17-((R)-6-hydroxy-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol AKOS028112978 [ Show all ]
Inchi Key	INBGSXNNRGWLJU-ZHHJOTBYSA-N
Inchi ID	InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1
PubChem CID	65094
ChEMBL	N/A
IUPHAR	2885
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553974	G-protein coupled receptor 183	P32249	GPR183	Homo sapiens (Human)	361

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