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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7alpha, 27-OHC
Molecular formula	C27H46O3
IUPAC name	(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R,6R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
Molecular weight	418.662
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	6.0
Synonyms	(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R,6R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol (25R)-7alpha,27-dihydroxycholesterol 7alpha,27-OHC (25R)-cholest-5-ene-3beta,7alpha,27-triol GTPL4353 (25R)-cholest-5-en-3beta,7alpha,26-triol CHEBI:76592 (3beta,7alpha,25R)-cholest-5-ene-3,7,26-triol SCHEMBL17413740 (25R)-7alpha,26-dihydroxycholesterol (25R)-cholest-5-ene-3beta,7alpha,26-triol D04BOQ [ Show all ]
Inchi Key	RXMHNAKZMGJANZ-GNENNHQYSA-N
Inchi ID	InChI=1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17-,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
PubChem CID	15907756
ChEMBL	N/A
IUPHAR	4353
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554781	G-protein coupled receptor 183	P32249	GPR183	Homo sapiens (Human)	361

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