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Name | G-protein coupled receptor 183 |
---|---|
Species | Homo sapiens (Human) |
Gene | GPR183 |
Synonym | EBI2 {ECO:0000303|PubMed:8383238} lymphocyte-specific G protein-coupled receptor hEBI2 {ECO:0000303|PubMed:22875855} GPR183 G protein-coupled receptor 183 [ Show all ] |
Disease | N/A |
Length | 361 |
Amino acid sequence | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK |
UniProt | P32249 |
Protein Data Bank | N/A |
GPCR-HGmod model | P32249 |
3D structure model | This predicted structure model is from GPCR-EXP P32249. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3259470 |
IUPHAR | 81 |
DrugBank | N/A |
Name | CHEMBL3561800 |
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Molecular formula | C21H23ClN2O3 |
IUPAC name | (E)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-3-phenylprop-2-en-1-one;formic acid |
Molecular weight | 386.876 |
Hydrogen bond acceptor | 4 |
Hydrogen bond donor | 1 |
XlogP | None |
Synonyms | MLS-0472336.0001 |
Inchi Key | MSKKYQAPEQWBKY-YGCVIUNWSA-N |
Inchi ID | InChI=1S/C20H21ClN2O.CH2O2/c21-19-9-6-18(7-10-19)16-22-12-14-23(15-13-22)20(24)11-8-17-4-2-1-3-5-17;2-1-3/h1-11H,12-16H2;1H,(H,2,3)/b11-8+; |
PubChem CID | 71295869 |
ChEMBL | CHEMBL3561800 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | |
Lipinski's druglikeness | Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
IC50 | 98.4 nM | PubChem BioAssay data set | ChEMBL |
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