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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7alpha,25-Dihydroxycholesterol
Molecular formula	C27H46O3
IUPAC name	(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
Molecular weight	418.662
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	5.7
Synonyms	(3?,7?)-Cholest-5-ene-3,7,25-triol 7-alpha,25-Dihydroxycholesterol C15520 GTPL4350 ZINC6036327 3\|A,7\|A,25-Trihydroxycholest-5-ene 7alpha,25-Dihydroxycholesterol, >=98% (HPLC) Cholest-5-ene-3-b,7-a,25-triol 64907-22-8 AKOS032949724 Cholest-5-ene-3beta,7alpha,25-triol (3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol 7?,25-Dihydroxycholesterol CHEBI:37623 MolPort-044-561-082 7alpha,25-OHC Cholest-5-ene-3-beta,7-alpha,25-triol 7-a,25-Dihydroxycholesterol AOB5694 D02JXQ 3beta,7alpha,25-Trihydroxycholest-5-ene cholest-5-en-3beta,7alpha,25-triol SCHEMBL2486315 5-Cholesten-3beta,7alpha,25-triol 7alpha-25-OHC Cholest-5-ene-3b,7a,25-triol [ Show all ]
Inchi Key	BQMSKLCEWBSPPY-IKVTXIKFSA-N
Inchi ID	InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1
PubChem CID	11954197
ChEMBL	N/A
IUPHAR	4350
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553409	G-protein coupled receptor 183	P32249	GPR183	Homo sapiens (Human)	361

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