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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BUTACLAMOL
Molecular formula	C25H31NO
IUPAC name	6-tert-butyl-3-azapentacyclo[11.8.1.03,8.09,22.016,21]docosa-9,11,13(22),16,18,20-hexaen-6-ol
Molecular weight	361.529
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.0
Synonyms	L000016 BDBM86721 CHEMBL13035 AC1L1AZZ NSC_37459 3-tert-butyl-2,3,4,4a,8,9,13b,14-octahydro-1h-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-ol CTK5A3756 AC1Q7BEJ SCHEMBL122822 CAS_51152-91-1 [ Show all ]
Inchi Key	ZZJYIKPMDIWRSN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3
PubChem CID	1224
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86721
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
441235	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
441246	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
441240	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
441241	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
441239	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
441242	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
441245	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
441238	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
441247	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
441243	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
441236	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
441244	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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