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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CGS-12066A maleate salt
Molecular formula	C21H21F3N4O4
IUPAC name	but-2-enedioic acid;4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
Molecular weight	450.418
Hydrogen bond acceptor	10
Hydrogen bond donor	2
XlogP	None
Synonyms	HMS3370A13 HMS3394P09
Inchi Key	ZBPAHEUAJMCLRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H17F3N4.C4H4O4/c1-22-7-9-23(10-8-22)16-15-3-2-6-24(15)14-5-4-12(17(18,19)20)11-13(14)21-16;5-3(6)1-2-4(7)8/h2-6,11H,7-10H2,1H3;1-2H,(H,5,6)(H,7,8)
PubChem CID	123945
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
424510	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
424503	5-hydroxytryptamine receptor 1B	O08892	HTR1B	Cavia porcellus (Guinea pig)	389
424506	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
424501	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
424504	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
424502	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
424507	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
424508	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
424509	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
424511	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
424505	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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