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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

Name5-hydroxytryptamine receptor 1B
SpeciesCavia porcellus (Guinea pig)
GeneHTR1B
Synonym5-HT-1B
5-HT1B
Serotonin receptor 1B
DiseaseN/A for non-human GPCRs
Length389
Amino acid sequenceMGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQALCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICISLPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGVILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTT
UniProtO08892
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLN/A
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 23
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
43042D structureButanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1)C18H22N2O5346.3836 / 4N/AN/A
117442D structurepropranololC16H21NO2259.3493 / 23.0Yes
142462D structure180083-23-2C32H32N4O3520.6336 / 05.6No
237032D structureCID 73919914C17H27ClN4O338.883 / 4N/AN/A
266182D structureYohimbineC21H26N2O3354.454 / 22.9Yes
266502D structureCHEBI:48565C21H26N2O3354.454 / 22.9Yes
838562D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
955002D structureAnpirtolineC10H13ClN2S228.7383 / 12.8Yes
1239842D structureTERTATOLOLC16H25NO2S295.4414 / 22.7Yes
1603692D structureritanserinC27H25F2N3OS477.5746 / 05.2No
1639572D structurepindololC14H20N2O2248.3263 / 31.8Yes
1748552D structure1-Methyllysergic acid butanolamideC21H27N3O2353.4663 / 22.3Yes
1756482D structuresumatriptanC14H21N3O2S295.4014 / 20.9Yes
1971122D structureDihydroegotamineC33H37N5O5583.6896 / 32.4No
2843972D structureS33084C29H29N3O2451.574 / 14.8Yes
2891862D structureCyanopindololC16H21N3O2287.3634 / 32.0Yes
2902982D structureserotoninC10H12N2O176.2192 / 30.2Yes
2990462D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3759562D structure5-CarboxamidotryptamineC11H13N3O203.2452 / 3-0.6Yes
3861662D structureMetergoline phenylmethyl esterC25H29N3O2403.5263 / 13.8Yes
3998782D structureACMC-20b84vC10H10FNO2195.1934 / 11.2Yes
4071072D structure148672-13-3C29H31N5O3497.5997 / 14.9Yes
4245032D structureCGS-12066A maleate saltC21H21F3N4O4450.41810 / 2N/AN/A

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