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Name | 5-hydroxytryptamine receptor 1B |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | HTR1B |
Synonym | 5-HT-1B 5-HT1B Serotonin receptor 1B |
Disease | N/A for non-human GPCRs |
Length | 389 |
Amino acid sequence | MGNPEASCTPPAVLGSQTGLPHANVSAPPNNCSAPSHIYQDSIALPWKVLLVVLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAFTDLLVSILVMPISTMYTVTGRWTLGQALCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVGYSAKRTPRRAAGMIALVWVFSICISLPPFFWRQAKAEEEVLDCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPEVPCDSGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGVILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTT |
UniProt | O08892 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | N/A |
IUPHAR | N/A |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
4304 | Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1) | C18H22N2O5 | 346.383 | 6 / 4 | N/A | N/A |
11744 | propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
14246 | 180083-23-2 | C32H32N4O3 | 520.633 | 6 / 0 | 5.6 | No |
23703 | CID 73919914 | C17H27ClN4O | 338.88 | 3 / 4 | N/A | N/A |
26618 | Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
26650 | CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
83856 | Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
95500 | Anpirtoline | C10H13ClN2S | 228.738 | 3 / 1 | 2.8 | Yes |
123984 | TERTATOLOL | C16H25NO2S | 295.441 | 4 / 2 | 2.7 | Yes |
160369 | ritanserin | C27H25F2N3OS | 477.574 | 6 / 0 | 5.2 | No |
163957 | pindolol | C14H20N2O2 | 248.326 | 3 / 3 | 1.8 | Yes |
174855 | 1-Methyllysergic acid butanolamide | C21H27N3O2 | 353.466 | 3 / 2 | 2.3 | Yes |
175648 | sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
197112 | Dihydroegotamine | C33H37N5O5 | 583.689 | 6 / 3 | 2.4 | No |
284397 | S33084 | C29H29N3O2 | 451.57 | 4 / 1 | 4.8 | Yes |
289186 | Cyanopindolol | C16H21N3O2 | 287.363 | 4 / 3 | 2.0 | Yes |
290298 | serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
299046 | methiothepin | C20H24N2S2 | 356.546 | 4 / 0 | 4.2 | Yes |
375956 | 5-Carboxamidotryptamine | C11H13N3O | 203.245 | 2 / 3 | -0.6 | Yes |
386166 | Metergoline phenylmethyl ester | C25H29N3O2 | 403.526 | 3 / 1 | 3.8 | Yes |
399878 | ACMC-20b84v | C10H10FNO2 | 195.193 | 4 / 1 | 1.2 | Yes |
407107 | 148672-13-3 | C29H31N5O3 | 497.599 | 7 / 1 | 4.9 | Yes |
424503 | CGS-12066A maleate salt | C21H21F3N4O4 | 450.418 | 10 / 2 | N/A | N/A |
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