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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Cyanopindolol
Molecular formula	C16H21N3O2
IUPAC name	4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile
Molecular weight	287.363
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.0
Synonyms	BRD-A47884604-001-01-7 CYANOPINDOLOL(+/-) PDSP1_001094 69906-85-0 L000210 PDSP2_001585 (-)-Cyanopindolol AC1L4E3D NSC707473 SR-01000597973 1H-Indole-2-carbonitrile, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)- CAS_155346 D0X8ZA PDSP1_001601 (+-)-Cyanopindolol 81089-45-4 CHEMBL378501 NCI60_038172 RT-012114 BDBM81499 CYANOPINDOLOL HEMIFUMARATE NSC_155346 SR-01000597973-1 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile CHEBI:125406 GTPL132 PDSP2_001078 (+/-)4-(3-t-butylamino-2-hydroxypropoxy)-1h-indole-2-carbonitrile CTK8E9328 NSC-707473 SCHEMBL353756 [ Show all ]
Inchi Key	QXIUMMLTJVHILT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H21N3O2/c1-16(2,3)18-9-12(20)10-21-15-6-4-5-14-13(15)7-11(8-17)19-14/h4-7,12,18-20H,9-10H2,1-3H3
PubChem CID	155346
ChEMBL	CHEMBL378501
IUPHAR	132
BindingDB	81499
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
289183	5-hydroxytryptamine receptor 1B	P28334	Htr1b	Mus musculus (Mouse)	386
289185	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
289186	5-hydroxytryptamine receptor 1B	O08892	HTR1B	Cavia porcellus (Guinea pig)	389
289187	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
289181	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
289184	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
289188	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
556601	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
289182	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466

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