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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ICODEXTRIN
Molecular formula	C8H8Cl2N4
IUPAC name	2-[(2,6-dichlorophenyl)methylideneamino]guanidine
Molecular weight	231.08
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	1.7
Synonyms	MRF-0000008 SPBio_001991 Tox21_110932_1 2,6-dichlorobenzaldehyde guanylhydrazone CHEMBL1313657 DSSTox_RID_81042 KBio1_000010 NCGC00024846-08 Spectrum4_000567 DB-051784 FT-0635524 KBio2_006459 KBioSS_001323 Prestwick1_000096 SR-01000721838-5 AKOS017264577 DSSTox_CID_25666 Hydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-, (E)- N-(2,6-dichlorobenzylidene)-N'-amidino hydrazine Spectrum2_001114 WDZVGELJXXEGPV-UHFFFAOYSA-N 2-[(2,6-dichlorophenyl)methylideneamino]guanidine CTK4H1147 DTXSID6045666 KBio2_001323 NINDS_000010 Spectrum_000843 DB00629 HMS2233D12 KBio3_001310 MCULE-4615358259 SPBio_001248 Tox21_110932 1-(2,6-Dichlorobenzylideneamino)guanidine CAS-5051-62-7 DSSTox_GSID_45666 NCGC00024846-03 Spectrum3_000445 ZINC242701441 5051-62-7 D02YCH Extraneal KBio2_003891 Prestwick0_000096 SR-01000721838 AC1L1G45 DivK1c_000010 HMS3370A17 KBioGR_000974 [ Show all ]
Inchi Key	WDZVGELJXXEGPV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)
PubChem CID	3517
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81979, 96725
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557027	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
371103	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
371100	Alpha-2A adrenergic receptor	P18871	ADRA2A	Sus scrofa (Pig)	450
371102	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
371101	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
371098	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
371104	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
371099	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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