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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	4-Methylhistamine
Molecular formula	C6H11N3
IUPAC name	2-(5-methyl-1H-imidazol-4-yl)ethanamine
Molecular weight	125.175
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	-0.2
Synonyms	AN-9442 EN300-82322 MolPort-006-803-984 UNII-54ST71P9EE 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine 36507-31-0 5-Methyl-1H-imidazole-4-ethanamine Hydrochloride C17929 IMIDAZOLE, 4-(2-AMINOETHYL)-5-METHYL- PDSP2_000398 2-(5-METHYL-3H-IMIDAZOL-4-YL)-ETHYLAMINE AB45417 AKOS022477289 CHEMBL275443 MCULE-8926131767 SCHEMBL606803 2-(4-METHYL-1H-IMIDAZOL-5-YL)ETHAN-1-AMINE 5-(2-Aminoethyl)-4-methylimidazole BDBM22880 FT-0736440 p-methylhistamine ZINC3605034 2-(5-methyl-1H-imidazol-4-yl)ethanamine 4-Methyl Histamine Dihydrochloride 5-Methylhistamine AC1L1XS2 CHEBI:74760 L000072 SC-51140 1H-Imidazo-4-ethanamine, 5-methyl- 2-(5-Methyl-4-imidazolyl)ethylamine 5(4)-Methylhistamine ALBB-030504 D02SQF Methylhistamine-4 UGYXPZQILZRKJJ-UHFFFAOYSA-N 2-(4-METHYL-1H-IMIDAZOL-5-YL)ETHANAMINE 36376-47-3 (di-hydrochloride) 5-Methyl-1H-imidazole-4-ethanamine BRD-K70821460-300-01-6 GTPL1269 PDSP1_000400 2-(5-Methyl-1H-imidazol-4-yl)ethylamine # 4-Methyl-1H-imidazole-5-ethanamine 54ST71P9EE AKOS012036768 LS-78033 SCHEMBL11452941 1H-Imidazole-4-ethanamine, 5-methyl- 2-(5-Methyl-4-imidazolyl)ethylamine Dihydrochloride 5(4)-Methylhistamine Dihydrochloride [ Show all ]
Inchi Key	UGYXPZQILZRKJJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9)
PubChem CID	37463
ChEMBL	CHEMBL275443
IUPHAR	1269
BindingDB	22880
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
336613	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
455069	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
336615	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
336616	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
336618	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
336612	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
336614	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
336617	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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