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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL458220
Molecular formula	C29H28ClN5O2
IUPAC name	N-[3-[(5-chloro-6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]-2-methylphenyl]-4-phenylbenzamide
Molecular weight	514.026
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	4.3
Synonyms	BDBM50412985 SCHEMBL1162417
Inchi Key	OZAJLQLEAWUZSC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H28ClN5O2/c1-20-24(19-35-29(37)27(30)26(18-32-35)34-16-14-31-15-17-34)8-5-9-25(20)33-28(36)23-12-10-22(11-13-23)21-6-3-2-4-7-21/h2-13,18,31H,14-17,19H2,1H3,(H,33,36)
PubChem CID	44581974
ChEMBL	CHEMBL458220
IUPHAR	N/A
BindingDB	50412985
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
253737	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
253739	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
253738	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
253735	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
253733	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
253734	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
253741	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
253740	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
253732	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
253736	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
253731	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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