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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Deltorphin II
Molecular formula	C38H54N8O10
IUPAC name	(4S)-4-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
Molecular weight	782.896
Hydrogen bond acceptor	11
Hydrogen bond donor	10
XlogP	-1.3
Synonyms	(S)-5-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-4-((S)-2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)-3-phenylpropanamido)-5-oxopentanoic acid C18095 Deltorphin-II Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide 4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid (deltorphin B) CHEMBL20226 H2N-Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2 ZINC95628075 BDBM50000507 Deltorphin B MolPort-003-959-650 [D-Ala2]-Deltorphin II, >=97% (HPLC) 122752-16-3 CHEBI:81498 DELTORPHINII Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2 CS-7608 HY-P1013 [D-Ala2]-Deltorphin II (S)-4-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid C-54172 NCGC00167311-01 4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-4-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-butyric acid FT-0771833 Tyr-D-Ala-Phe-Glu-Val-Val-GlyNH2 AKOS024456444 Deltorphin 2 MFCD00080072 [D-Ala2]-Deltorphin II, >97%, powder [ Show all ]
Inchi Key	NUNBRHVOPFWRRG-RCEFDBTISA-N
Inchi ID	InChI=1S/C38H54N8O10/c1-20(2)31(37(55)41-19-29(40)48)46-38(56)32(21(3)4)45-35(53)27(15-16-30(49)50)43-36(54)28(18-23-9-7-6-8-10-23)44-33(51)22(5)42-34(52)26(39)17-24-11-13-25(47)14-12-24/h6-14,20-22,26-28,31-32,47H,15-19,39H2,1-5H3,(H2,40,48)(H,41,55)(H,42,52)(H,43,54)(H,44,51)(H,45,53)(H,46,56)(H,49,50)/t22-,26+,27+,28+,31+,32+/m1/s1
PubChem CID	10033203
ChEMBL	CHEMBL20226
IUPHAR	N/A
BindingDB	50000507
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
232492	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
232493	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
461233	Delta-type opioid receptor	P79291	OPRD1	Sus scrofa (Pig)	228
491782	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
232494	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
232495	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
491780	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
491781	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
556390	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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