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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LP-12
Molecular formula	C32H39N3O
IUPAC name	6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	481.684
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	CHEMBL243954 6-[4-(2-phenylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide GTPL8434 BDBM21383 Piperazinehexanamide derivative, 21 4-(2-Biphenylyl)-N-(1,2,3,4-tetrahydronaphthalene-1-yl)piperazine-1-hexanamide compound 21 [PMID 17649988] 1185136-22-4 6-(4-([1,1'-biphenyl]-2-yl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide D0Z1OF AKOS027422832 NCGC00186032-01 [ Show all ]
Inchi Key	NMZIDFFHGCRAJV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H39N3O/c36-32(33-30-18-11-15-26-14-6-7-16-28(26)30)20-5-2-10-21-34-22-24-35(25-23-34)31-19-9-8-17-29(31)27-12-3-1-4-13-27/h1,3-4,6-9,12-14,16-17,19,30H,2,5,10-11,15,18,20-25H2,(H,33,36)
PubChem CID	23643664
ChEMBL	CHEMBL243954
IUPHAR	8434
BindingDB	21383
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
227410	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
227413	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
554407	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
227408	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
227412	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
554408	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
227409	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
227415	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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