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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MPEP
Molecular formula	C14H11N
IUPAC name	2-methyl-6-(2-phenylethynyl)pyridine
Molecular weight	193.249
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	3.3
Synonyms	7VC0YVI27Y BRD-K60690191-003-02-1 DB-014655 Lopac-M-5435 NCGC00015682-03 s2809 ZX-AN014840 2-Methyl-6-(phenylethynyl)pyridine 2-Picoline, 6-phenylethynyl- AC1MHGB1 GTPL1426 MLS006011229 NCGC00025044-01 SW219533-1 6-methyl-2-(2-phenylethynyl)pyridine BCP05962 D0IO8J KB-78955 NCGC00015682-01 Pyridine, 2-methyl-6-(2-phenylethynyl)- Y0463 2-methyl-6-(phenyl-ethynyl)pyridine 2-Methyl-6-phenylethynyl-pyridine 96206-92-7 CCG-204823 DTXSID9043982 Lopac0_000738 NCGC00015682-04 SCHEMBL103061 [3H]-2-methyl-6-(phenylethynyl)-pyridine 2151AH AKOS006275850 CHEMBL66654 HMS3651F13 MolPort-003-958-770 NCGC00025044-02 Tocris-1212 6-Methyl-2-(phenylethynyl)pyridine BDBM50084137 D0R8TZ L000408 NCGC00015682-02 Pyridine, 2-methyl-6-(phenylethynyl)- ZINC2581406 2-methyl-6-(phenylethynyl)-pyridine 2-Methyl-6-phenylethynyl-pyridine(MPEP) AB0035962 CHEBI:64159 F2167-5303 LS-131827 NCGC00015682-05 SMR004702989 AM81262 CS-0794 HY-14609A NCGC00025044-03 UNII-7VC0YVI27Y 2-methyl-6-(2-phenylethynyl)pyridine [ Show all ]
Inchi Key	NEWKHUASLBMWRE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
PubChem CID	3025961
ChEMBL	CHEMBL66654
IUPHAR	1426
BindingDB	50084137
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
221646	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
221640	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
221641	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
221635	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
221644	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
221647	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
221636	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
221637	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
221638	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
221642	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
221639	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
221645	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908
221643	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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