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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	alpha-methyl-5-HT
Molecular formula	C11H14N2O
IUPAC name	3-(2-aminopropyl)-1H-indol-5-ol
Molecular weight	190.246
Hydrogen bond acceptor	2
Hydrogen bond donor	3
XlogP	0.6
Synonyms	AKOS022643479 BPBio1_001083 FT-0645249 NCGC00015629-05 alpha-Me-5-HT CHEBI:48295 Lopac0_000823 PDSP1_001117 BDBM50014945 CTK6A6964 NCGC00015629-03 PDSP2_001662 Alpha Methyl 5 Hydroxytryptamine BRD-A17745711-103-01-0 GTPL152 NCGC00024651-02 LYPCGXKCQDYTFV-UHFFFAOYSA-N PDSP1_001679 AC1L1CXO Biomol-NT_000085 D09OYA NCGC00015629-04 SCHEMBL396996 alpha-M-5-HT CCG-204907 L001159 NCGC00024651-03 3-(2-aminopropyl)-1H-indol-5-ol alpha-Methylserotonin CHEMBL275854 MB03476 PDSP2_001101 [ Show all ]
Inchi Key	LYPCGXKCQDYTFV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3
PubChem CID	2107
ChEMBL	CHEMBL275854
IUPHAR	152
BindingDB	50014945
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199570	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
199583	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
199581	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
199584	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
199568	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
199579	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
199575	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
199574	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
199577	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
199567	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
199571	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
199572	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
199573	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
199576	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
554292	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
554293	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
554291	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
199582	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446

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