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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB-269970
Molecular formula	C18H28N2O3S
IUPAC name	3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol
Molecular weight	352.493
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BCPP000080 D0IT3X Lopac0_001059 [3H]SB269970 2921AH 3-{(R)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol AC1O7H0E CCG-205136 FT-0771258 NCGC00025229-03 SB269970 (R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol (SB-269970) AKOS024465019 CHEMBL282199 HY-15370 SB 269970 Tocris-1612 (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonylphenol BDBM50098551 D0YP7L NCGC00025229-01 SB-269970-A 3-{(S)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol AJ-47584 CHEBI:92426 GTPL3233 Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)- SCHEMBL375474 (r)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol AX8294918 CS-1645 KB-80497 SB-269,970 ZINC3982174 201038-74-6 3-[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidine-1-sulfonyl]phenol AB0048092 BRD-K24201553-003-02-4 NCGC00025229-02 SB19510 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol AK163801 GTPL3247 Pyrrolidine,1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-Methyl-1-piperidinyl)ethyl)-,(R)- ST24035398 (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol [ Show all ]
Inchi Key	HWKROQUZSKPIKQ-MRXNPFEDSA-N
Inchi ID	InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1
PubChem CID	6604889
ChEMBL	CHEMBL282199
IUPHAR	3247, 3233
BindingDB	50098551
DrugBank	DB13988
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
125649	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
125661	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
125660	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
125663	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
125657	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
125659	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
125666	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
125667	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
125654	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
125656	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
125655	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
125662	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
125658	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
125650	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
125651	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
125652	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
125664	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
125665	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
125653	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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