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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-methyl-N-[2-methyl-1-(phenylcarbonyl)-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylpropanamide
Molecular formula	C27H28N2O2
IUPAC name	N-(1-benzoyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl)-2-methyl-N-phenylpropanamide
Molecular weight	412.533
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	5.4
Synonyms	AKOS001950167 MCULE-7813287848 SCHEMBL5397963 AKOS022077697 MolPort-002-939-186 AC1MWFTS STK063474 BDBM86692 N-(1-benzoyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl)-2-methyl-N-phenylpropanamide [ Show all ]
Inchi Key	FTCWKSGDHXCEMZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N2O2/c1-19(2)26(30)29(22-14-8-5-9-15-22)25-18-20(3)28(24-17-11-10-16-23(24)25)27(31)21-12-6-4-7-13-21/h4-17,19-20,25H,18H2,1-3H3
PubChem CID	3723424
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86692
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
555790	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
86626	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
86625	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
86631	Cysteinyl leukotriene receptor 1	Q9Y271	CYSLTR1	Homo sapiens (Human)	337
86624	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
555788	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
86630	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
86628	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
555789	Leukotriene B4 receptor 2	Q9NPC1	LTB4R2	Homo sapiens (Human)	358
86629	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
86632	Platelet-activating factor receptor	P25105	PTAFR	Homo sapiens (Human)	342
86627	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
555787	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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