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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL328573
Molecular formula	C19H22N2O
IUPAC name	N,N-dimethyl-1-[(4S,6R)-3-oxa-2-azatetracyclo[12.4.0.02,6.07,12]octadeca-1(18),7,9,11,14,16-hexaen-4-yl]methanamine
Molecular weight	294.398
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.9
Synonyms	N,N-Dimethyl-2,3,3abeta,8-tetrahydro-1-oxa-12b-azadibenzo[e,h]azulene-2alpha-methanamine SCHEMBL7858917 BDBM50146360 Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine
Inchi Key	BTSCZNWXJQSJIE-QFBILLFUSA-N
Inchi ID	InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1
PubChem CID	9839081
ChEMBL	CHEMBL328573
IUPHAR	N/A
BindingDB	50146360
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32636	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
32635	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
32631	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
32630	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
32641	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
32633	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
32632	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
32642	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
32637	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
32639	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
32638	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
32640	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
32634	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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