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Name | Type-1 angiotensin II receptor |
---|---|
Species | Cavia porcellus (Guinea pig) |
Gene | AGTR1 |
Synonym | Angiotensin II type-1 receptor AT1 |
Disease | N/A for non-human GPCRs |
Length | 359 |
Amino acid sequence | MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE |
UniProt | Q9WV26 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1671613 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
5956 | ![]() | C26H20F3N5O | 475.475 | 8 / 1 | 6.2 | No |
13178 | ![]() | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
16478 | ![]() | C25H25N5O | 411.509 | 5 / 1 | 5.2 | No |
19388 | ![]() | C24H23N5O2 | 413.481 | 6 / 1 | 4.1 | Yes |
22683 | ![]() | C26H26N6O | 438.535 | 5 / 1 | 4.2 | Yes |
25019 | ![]() | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
25785 | ![]() | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
28515 | ![]() | C24H23N5O | 397.482 | 5 / 1 | 4.7 | Yes |
28901 | ![]() | C22H21N5O | 371.444 | 5 / 1 | 4.3 | Yes |
42192 | ![]() | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
43575 | ![]() | C23H22IN5O | 511.367 | 5 / 1 | 5.5 | No |
46804 | ![]() | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
54319 | ![]() | C24H19NO3 | 369.42 | 4 / 1 | 5.2 | No |
58890 | ![]() | C28H23N5O2 | 461.525 | 6 / 1 | 5.3 | No |
59085 | ![]() | C25H21N5 | 391.478 | 4 / 1 | 5.6 | No |
61461 | ![]() | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
75307 | ![]() | C26H25N5O3 | 455.518 | 7 / 2 | 4.7 | Yes |
77614 | ![]() | C24H23N5O3 | 429.48 | 7 / 1 | 4.2 | Yes |
80203 | ![]() | C27H27N5O2 | 453.546 | 6 / 1 | 4.9 | Yes |
86118 | ![]() | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
86195 | ![]() | C26H20F3N5O | 475.475 | 8 / 1 | 6.2 | No |
98417 | ![]() | C21H18IN5O | 483.313 | 5 / 1 | 4.6 | Yes |
101989 | ![]() | C23H17N5O | 379.423 | 5 / 1 | 4.5 | Yes |
103992 | ![]() | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
104943 | ![]() | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
126414 | ![]() | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
128901 | ![]() | C24H22N3O4- | 416.457 | 5 / 1 | 5.3 | No |
131473 | ![]() | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
132088 | ![]() | C25H24FN5O | 429.499 | 6 / 1 | 5.3 | No |
132505 | ![]() | C25H21NO3 | 383.447 | 4 / 1 | 5.6 | No |
132524 | ![]() | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
137575 | ![]() | C25H20N4O | 392.462 | 4 / 1 | 5.8 | No |
142457 | ![]() | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
149507 | ![]() | C29H25N5O2 | 475.552 | 6 / 1 | 5.7 | No |
150067 | ![]() | C22H25ClN6O | 424.933 | 5 / 2 | 3.2 | Yes |
166652 | ![]() | C25H24ClN5O | 445.951 | 5 / 1 | 5.8 | No |
168041 | ![]() | C24H22N3NaO4 | 439.447 | 5 / 1 | N/A | N/A |
179384 | ![]() | C27H25NO3 | 411.501 | 4 / 1 | 6.5 | No |
187922 | ![]() | C23H21N5O2 | 399.454 | 6 / 1 | 3.6 | Yes |
202818 | ![]() | C22H22ClN6O- | 421.909 | 6 / 1 | 3.7 | Yes |
206607 | ![]() | C23H17N5S | 395.484 | 5 / 1 | 5.5 | No |
207791 | ![]() | C27H24FN5O2 | 469.52 | 7 / 1 | 5.6 | No |
210731 | ![]() | C25H24ClN5O | 445.951 | 5 / 1 | 5.8 | No |
214639 | ![]() | C25H25N5O3 | 443.507 | 7 / 1 | 4.6 | Yes |
214662 | ![]() | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
216130 | ![]() | C25H25N5O3 | 443.507 | 7 / 1 | 4.7 | Yes |
221384 | ![]() | C26H22N6O | 434.503 | 6 / 1 | 4.5 | Yes |
227232 | ![]() | C23H23N5O2 | 401.47 | 6 / 1 | 3.6 | Yes |
228160 | ![]() | C26H23NO3 | 397.474 | 4 / 1 | 6.0 | No |
228916 | ![]() | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
230614 | ![]() | C26H23N5O | 421.504 | 5 / 1 | 5.7 | No |
234322 | ![]() | C24H19N5S | 409.511 | 5 / 1 | 5.4 | No |
235937 | ![]() | C27H23N5O | 433.515 | 5 / 1 | 5.6 | No |
240191 | ![]() | C24H23N5O3 | 429.48 | 7 / 1 | 4.2 | Yes |
247474 | ![]() | C22H21N5O2 | 387.443 | 6 / 2 | 3.1 | Yes |
252374 | ![]() | C22H22ClKN6O | 461.007 | 6 / 1 | N/A | N/A |
260104 | ![]() | C23H21N5O3 | 415.453 | 7 / 1 | 3.8 | Yes |
267625 | ![]() | C22H23ClN6O | 422.917 | 5 / 2 | 4.3 | Yes |
275076 | ![]() | C21H19N5O | 357.417 | 5 / 1 | 4.0 | Yes |
275512 | ![]() | C24H19N5O | 393.45 | 5 / 1 | 4.9 | Yes |
276387 | ![]() | C26H27N5O | 425.536 | 5 / 1 | 5.8 | No |
289825 | ![]() | C25H25N5O3 | 443.507 | 7 / 1 | 4.6 | Yes |
291769 | ![]() | C27H27N5O3 | 469.545 | 7 / 1 | 5.1 | No |
292825 | ![]() | C27H22F3N5O2 | 505.501 | 9 / 1 | 6.4 | No |
325673 | ![]() | C26H27N5O | 425.536 | 5 / 1 | 5.6 | No |
345701 | ![]() | C23H18N6O | 394.438 | 6 / 1 | 4.4 | Yes |
346041 | ![]() | C22H23ClN2O3 | 398.887 | 4 / 2 | 4.6 | Yes |
346439 | ![]() | C25H19N5 | 389.462 | 4 / 1 | 5.7 | No |
346440 | ![]() | C25H19N5 | 389.462 | 4 / 1 | 5.7 | No |
350466 | ![]() | C27H23N5O3 | 465.513 | 7 / 1 | 5.2 | No |
356525 | ![]() | C22H19N5O3 | 401.426 | 7 / 2 | 3.5 | Yes |
362146 | ![]() | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
364032 | ![]() | C24H26N6O3 | 446.511 | 7 / 3 | 3.2 | Yes |
375668 | ![]() | C28H27N5O2 | 465.557 | 6 / 1 | 6.1 | No |
379884 | ![]() | C28H25N5O | 447.542 | 5 / 1 | 5.9 | No |
406545 | ![]() | C26H27N5O | 425.536 | 5 / 1 | 5.6 | No |
412666 | ![]() | C22H19N5O2 | 385.427 | 6 / 1 | 3.4 | Yes |
417379 | ![]() | C24H18ClN5O | 427.892 | 5 / 1 | 5.5 | No |
421829 | ![]() | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
428674 | ![]() | C26H23N5O | 421.504 | 5 / 1 | 5.7 | No |
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