You can:
| Name | Type-1 angiotensin II receptor |
|---|---|
| Species | Cavia porcellus (Guinea pig) |
| Gene | AGTR1 |
| Synonym | Angiotensin II type-1 receptor AT1 |
| Disease | N/A for non-human GPCRs |
| Length | 359 |
| Amino acid sequence | MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE |
| UniProt | Q9WV26 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL1671613 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 5956 |  CHEMBL129194 | C26H20F3N5O | 475.475 | 8 / 1 | 6.2 | No |
| 13178 |  CHEMBL337446 | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
| 16478 |  UNII-V85UF0B9WX | C25H25N5O | 411.509 | 5 / 1 | 5.2 | No |
| 19388 |  CHEMBL22879 | C24H23N5O2 | 413.481 | 6 / 1 | 4.1 | Yes |
| 22683 |  ZD-7155 | C26H26N6O | 438.535 | 5 / 1 | 4.2 | Yes |
| 25019 |  CHEMBL87603 | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
| 25785 |  CHEMBL86495 | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
| 28515 |  CHEMBL283110 | C24H23N5O | 397.482 | 5 / 1 | 4.7 | Yes |
| 28901 |  CHEMBL22387 | C22H21N5O | 371.444 | 5 / 1 | 4.3 | Yes |
| 42192 |  CHEMBL128397 | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
| 43575 |  CHEMBL285560 | C23H22IN5O | 511.367 | 5 / 1 | 5.5 | No |
| 46804 |  CHEMBL338900 | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
| 54319 |  CHEMBL132269 | C24H19NO3 | 369.42 | 4 / 1 | 5.2 | No |
| 58890 |  CHEMBL280189 | C28H23N5O2 | 461.525 | 6 / 1 | 5.3 | No |
| 59085 |  CHEMBL423370 | C25H21N5 | 391.478 | 4 / 1 | 5.6 | No |
| 61461 |  CHEMBL130455 | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
| 75307 |  CHEMBL89846 | C26H25N5O3 | 455.518 | 7 / 2 | 4.7 | Yes |
| 77614 |  CHEMBL283579 | C24H23N5O3 | 429.48 | 7 / 1 | 4.2 | Yes |
| 80203 |  CHEMBL89143 | C27H27N5O2 | 453.546 | 6 / 1 | 4.9 | Yes |
| 86118 |  UNII-23B5RBZGBD | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
| 86195 |  CHEMBL434615 | C26H20F3N5O | 475.475 | 8 / 1 | 6.2 | No |
| 98417 |  CHEMBL22391 | C21H18IN5O | 483.313 | 5 / 1 | 4.6 | Yes |
| 101989 |  CHEMBL339592 | C23H17N5O | 379.423 | 5 / 1 | 4.5 | Yes |
| 103992 |  CHEMBL341223 | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
| 104943 |  CHEMBL334431 | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
| 126414 |  CHEMBL337380 | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
| 128901 |  CHEMBL1668010 | C24H22N3O4- | 416.457 | 5 / 1 | 5.3 | No |
| 131473 |  CHEMBL87034 | C26H27N5O2 | 441.535 | 6 / 1 | 5.2 | No |
| 132088 |  CHEMBL314982 | C25H24FN5O | 429.499 | 6 / 1 | 5.3 | No |
| 132505 |  CHEMBL339846 | C25H21NO3 | 383.447 | 4 / 1 | 5.6 | No |
| 132524 |  CHEMBL131050 | C26H20N6O | 432.487 | 6 / 1 | 5.0 | Yes |
| 137575 |  CHEMBL130858 | C25H20N4O | 392.462 | 4 / 1 | 5.8 | No |
| 142457 |  CHEMBL132115 | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
| 149507 |  CHEMBL434768 | C29H25N5O2 | 475.552 | 6 / 1 | 5.7 | No |
| 150067 |  BDBM50009714 | C22H25ClN6O | 424.933 | 5 / 2 | 3.2 | Yes |
| 166652 |  CHEMBL314859 | C25H24ClN5O | 445.951 | 5 / 1 | 5.8 | No |
| 168041 |  CHEMBL1668010 | C24H22N3NaO4 | 439.447 | 5 / 1 | N/A | N/A |
| 179384 |  CHEMBL128332 | C27H25NO3 | 411.501 | 4 / 1 | 6.5 | No |
| 187922 |  CHEMBL22908 | C23H21N5O2 | 399.454 | 6 / 1 | 3.6 | Yes |
| 202818 |  Cozaar | C22H22ClN6O- | 421.909 | 6 / 1 | 3.7 | Yes |
| 206607 |  CHEMBL142860 | C23H17N5S | 395.484 | 5 / 1 | 5.5 | No |
| 207791 |  CHEMBL128389 | C27H24FN5O2 | 469.52 | 7 / 1 | 5.6 | No |
| 210731 |  CHEMBL84792 | C25H24ClN5O | 445.951 | 5 / 1 | 5.8 | No |
| 214639 |  CHEMBL21968 | C25H25N5O3 | 443.507 | 7 / 1 | 4.6 | Yes |
| 214662 |  CHEMBL128536 | C25H21N5O | 407.477 | 5 / 1 | 5.3 | No |
| 216130 |  CHEMBL432459 | C25H25N5O3 | 443.507 | 7 / 1 | 4.7 | Yes |
| 221384 |  CHEMBL22945 | C26H22N6O | 434.503 | 6 / 1 | 4.5 | Yes |
| 227232 |  CHEMBL283770 | C23H23N5O2 | 401.47 | 6 / 1 | 3.6 | Yes |
| 228160 |  CHEMBL338048 | C26H23NO3 | 397.474 | 4 / 1 | 6.0 | No |
| 228916 |  CHEMBL130540 | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
| 230614 |  CHEMBL132509 | C26H23N5O | 421.504 | 5 / 1 | 5.7 | No |
| 234322 |  CHEMBL141447 | C24H19N5S | 409.511 | 5 / 1 | 5.4 | No |
| 235937 |  CHEMBL281192 | C27H23N5O | 433.515 | 5 / 1 | 5.6 | No |
| 240191 |  CHEMBL283742 | C24H23N5O3 | 429.48 | 7 / 1 | 4.2 | Yes |
| 247474 |  CHEMBL283372 | C22H21N5O2 | 387.443 | 6 / 2 | 3.1 | Yes |
| 252374 |  LOSARTAN POTASSIUM | C22H22ClKN6O | 461.007 | 6 / 1 | N/A | N/A |
| 260104 |  CHEMBL22426 | C23H21N5O3 | 415.453 | 7 / 1 | 3.8 | Yes |
| 267625 |  losartan | C22H23ClN6O | 422.917 | 5 / 2 | 4.3 | Yes |
| 275076 |  CHEMBL281999 | C21H19N5O | 357.417 | 5 / 1 | 4.0 | Yes |
| 275512 |  CHEMBL142380 | C24H19N5O | 393.45 | 5 / 1 | 4.9 | Yes |
| 276387 |  CHEMBL428711 | C26H27N5O | 425.536 | 5 / 1 | 5.8 | No |
| 289825 |  CHEMBL22692 | C25H25N5O3 | 443.507 | 7 / 1 | 4.6 | Yes |
| 291769 |  CHEMBL86858 | C27H27N5O3 | 469.545 | 7 / 1 | 5.1 | No |
| 292825 |  CHEMBL341210 | C27H22F3N5O2 | 505.501 | 9 / 1 | 6.4 | No |
| 325673 |  CHEMBL86604 | C26H27N5O | 425.536 | 5 / 1 | 5.6 | No |
| 345701 |  CHEMBL1668124 | C23H18N6O | 394.438 | 6 / 1 | 4.4 | Yes |
| 346041 |  Exp7711 | C22H23ClN2O3 | 398.887 | 4 / 2 | 4.6 | Yes |
| 346439 |  CHEMBL336056 | C25H19N5 | 389.462 | 4 / 1 | 5.7 | No |
| 346440 |  CID 49823959 | C25H19N5 | 389.462 | 4 / 1 | 5.7 | No |
| 350466 |  CHEMBL129872 | C27H23N5O3 | 465.513 | 7 / 1 | 5.2 | No |
| 356525 |  CHEMBL25220 | C22H19N5O3 | 401.426 | 7 / 2 | 3.5 | Yes |
| 362146 |  CHEMBL128644 | C26H23N5O2 | 437.503 | 6 / 1 | 5.3 | No |
| 364032 |  Olmesartan | C24H26N6O3 | 446.511 | 7 / 3 | 3.2 | Yes |
| 375668 |  CHEMBL337955 | C28H27N5O2 | 465.557 | 6 / 1 | 6.1 | No |
| 379884 |  CHEMBL23006 | C28H25N5O | 447.542 | 5 / 1 | 5.9 | No |
| 406545 |  CHEMBL89614 | C26H27N5O | 425.536 | 5 / 1 | 5.6 | No |
| 412666 |  CHEMBL22837 | C22H19N5O2 | 385.427 | 6 / 1 | 3.4 | Yes |
| 417379 |  CHEMBL130275 | C24H18ClN5O | 427.892 | 5 / 1 | 5.5 | No |
| 421829 |  CHEMBL336167 | C25H20ClN5O | 441.919 | 5 / 1 | 6.0 | No |
| 428674 |  CHEMBL337017 | C26H23N5O | 421.504 | 5 / 1 | 5.7 | No |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417