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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Cavia porcellus (Guinea pig)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
UniProt	Q9WV26
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1671613
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL339846
Molecular formula	C25H21NO3
IUPAC name	2-[4-[(2-ethylquinolin-4-yl)oxymethyl]phenyl]benzoic acid
Molecular weight	383.447
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.6
Synonyms	SCHEMBL9177090 4''-(2-Ethyl-quinolin-4-yloxymethyl)-biphenyl-2-carboxylic acid 4'-[(2-ethylquinolin-4-yloxy)methyl]biphenyl-2-carboxylic acid BDBM50003381 IGFIMRXLCYJXCW-UHFFFAOYSA-N 4'-[[(2-Ethylquinolin-4-yl)oxy]methyl]-1,1'-biphenyl-2-carboxylic acid [ Show all ]
Inchi Key	IGFIMRXLCYJXCW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H21NO3/c1-2-19-15-24(22-9-5-6-10-23(22)26-19)29-16-17-11-13-18(14-12-17)20-7-3-4-8-21(20)25(27)28/h3-15H,2,16H2,1H3,(H,27,28)
PubChem CID	10475047
ChEMBL	CHEMBL339846
IUPHAR	N/A
BindingDB	50003381
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	170.0 nM	PMID1433210	BindingDB,ChEMBL

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