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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Cavia porcellus (Guinea pig)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MILNSSTEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADICFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCVIIWLMAGLASLPAVIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFMFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSTLSTKMSTLSYRPSDNVSSSAKKPVQCFEVE
UniProt	Q9WV26
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1671613
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL338048
Molecular formula	C26H23NO3
IUPAC name	2-[4-[(2-propylquinolin-4-yl)oxymethyl]phenyl]benzoic acid
Molecular weight	397.474
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.0
Synonyms	4'-[[(2-Propylquinolin-4-yl)oxy]methyl]-1,1'-biphenyl-2-carboxylic acid 4''-(2-Propyl-quinolin-4-yloxymethyl)-biphenyl-2-carboxylic acid SCHEMBL9183186 4'-[(2-Propylquinolin-4-yloxy)methyl]biphenyl-2-carboxylic acid BDBM50003393 NOBNOIVDXOQHJK-UHFFFAOYSA-N [ Show all ]
Inchi Key	NOBNOIVDXOQHJK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23NO3/c1-2-7-20-16-25(23-10-5-6-11-24(23)27-20)30-17-18-12-14-19(15-13-18)21-8-3-4-9-22(21)26(28)29/h3-6,8-16H,2,7,17H2,1H3,(H,28,29)
PubChem CID	11741515
ChEMBL	CHEMBL338048
IUPHAR	N/A
BindingDB	50003393
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	600.0 nM	PMID1433210	BindingDB,ChEMBL

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