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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL337380
Molecular formula	C26H20N6O
IUPAC name	2-ethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methoxy]quinoline-7-carbonitrile
Molecular weight	432.487
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.0
Synonyms	2-Ethyl-4-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline-7-carbonitrile BDBM50003390 4-[[2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-yl]methoxy]-2-ethylquinoline-7-carbonitrile
Inchi Key	HXMUQMOPAYNISW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H20N6O/c1-2-20-14-25(23-12-9-18(15-27)13-24(23)28-20)33-16-17-7-10-19(11-8-17)21-5-3-4-6-22(21)26-29-31-32-30-26/h3-14H,2,16H2,1H3,(H,29,30,31,32)
PubChem CID	10004855
ChEMBL	CHEMBL337380
IUPHAR	N/A
BindingDB	50003390
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
126414	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359

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