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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL128389
Molecular formula	C27H24FN5O2
IUPAC name	2-ethyl-6-(2-fluoroethoxy)-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methoxy]quinoline
Molecular weight	469.52
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.6
Synonyms	2-Ethyl-6-(2-fluoro-ethoxy)-4-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-quinoline BDBM50003382 SCHEMBL7838463 4-[[2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-yl]methoxy]-2-ethyl-6-(2-fluoroethoxy)quinoline
Inchi Key	MKPLRVPHRDVIRY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H24FN5O2/c1-2-20-15-26(24-16-21(34-14-13-28)11-12-25(24)29-20)35-17-18-7-9-19(10-8-18)22-5-3-4-6-23(22)27-30-32-33-31-27/h3-12,15-16H,2,13-14,17H2,1H3,(H,30,31,32,33)
PubChem CID	10368898
ChEMBL	CHEMBL128389
IUPHAR	N/A
BindingDB	50003382
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
207791	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359

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