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Name | Muscarinic acetylcholine receptor M2 |
---|---|
Species | Mus musculus (Mouse) |
Gene | Chrm2 |
Synonym | cholinergic receptor cholinergic receptor, muscarinic 2 AChR M2 Chrm-2 M2 muscarinic acetylcholine receptor [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 466 |
Amino acid sequence | MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGGTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDDNSRQTCIKIVTKTQKGDACTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR |
UniProt | Q9ERZ4 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL3197 |
IUPHAR | 14 |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
6609 | carbachol | C6H15ClN2O2 | 182.648 | 3 / 1 | N/A | N/A |
12722 | N,N'-Bis[2-[[5-(dimethylaminomethyl)-2-furanyl]methylthio]ethyl]-1-nitroethene-1,2-diamine | C22H35N5O4S2 | 497.673 | 10 / 2 | 2.7 | Yes |
22751 | BRN 5352858 | C18H28N2O2S2 | 368.554 | 6 / 0 | 2.5 | Yes |
25725 | 114724-56-0 | C9H13N3O | 179.223 | 4 / 0 | 0.8 | Yes |
25867 | BRN 5360513 | C24H32N2O2S2 | 444.652 | 6 / 0 | 3.8 | Yes |
28509 | CHEMBL542404 | C9H15ClN2O3 | 234.68 | 4 / 1 | N/A | N/A |
32445 | CHEMBL552656 | C12H21ClN2O3 | 276.761 | 4 / 1 | N/A | N/A |
34350 | CHEMBL553727 | C14H24ClN3O4 | 333.813 | 6 / 1 | N/A | N/A |
37029 | CHEMBL538467 | C6H11ClN2O2 | 178.616 | 3 / 2 | N/A | N/A |
37358 | CHEMBL74823 | C14H15ClN2O3 | 294.735 | 4 / 0 | 2.3 | Yes |
42822 | BRN 5358078 | C24H40N2O2S2 | 452.716 | 6 / 0 | 5.0 | Yes |
44049 | CHEMBL553865 | C12H21ClN2O2S | 292.822 | 4 / 1 | N/A | N/A |
56727 | BRN 5356180 | C21H34N2O2S2 | 410.635 | 6 / 0 | 3.5 | Yes |
61315 | CHEMBL540543 | C16H21ClN2O3 | 324.805 | 4 / 1 | N/A | N/A |
77894 | CHEMBL75380 | C10H16N2O2S | 228.31 | 4 / 0 | 1.1 | Yes |
97681 | CHEMBL554011 | C13H21ClN2O5 | 320.77 | 6 / 1 | N/A | N/A |
107035 | BRN 5834442 | C16H20N4O5S | 380.419 | 8 / 1 | 3.2 | Yes |
109797 | BRN 5836042 | C16H21N5O5S | 395.434 | 9 / 2 | 3.1 | Yes |
115815 | CHEMBL75045 | C14H16N2O2S | 276.354 | 4 / 0 | 2.3 | Yes |
116431 | arecoline | C8H13NO2 | 155.197 | 3 / 0 | 0.3 | Yes |
118986 | CHEMBL542406 | C10H17ClN2O3 | 248.707 | 4 / 1 | N/A | N/A |
131647 | CHEMBL542879 | C20H23Cl2N3O5 | 456.32 | 6 / 2 | N/A | N/A |
144919 | CHEMBL542886 | C8H13ClN2O3 | 220.653 | 4 / 2 | N/A | N/A |
148682 | BDBM50005504 | C22H35N5O4S2 | 497.673 | 10 / 1 | 1.9 | Yes |
156831 | CHEMBL76063 | C11H16N2O5 | 256.258 | 6 / 0 | 0.0 | Yes |
193481 | BRN 5365697 | C22H34N6O2S2 | 478.674 | 8 / 2 | 1.8 | Yes |
197053 | CHEMBL553520 | C10H17ClN2O3 | 248.707 | 4 / 1 | N/A | N/A |
206835 | CHEMBL543832 | C14H23ClN2O5 | 334.797 | 6 / 1 | N/A | N/A |
217465 | BRN 5359326 | C25H42N2O2S2 | 466.743 | 6 / 0 | 5.5 | No |
228661 | BRN 5357514 | C23H38N2O2S2 | 438.689 | 6 / 0 | 4.4 | Yes |
251623 | BRN 5369860 | C26H36N6O6S2 | 592.73 | 12 / 2 | 4.9 | No |
260547 | physostigmine | C15H21N3O2 | 275.352 | 4 / 1 | 0.7 | Yes |
261024 | BRN 5837136 | C16H22N6O5S | 410.449 | 10 / 3 | 3.0 | Yes |
281281 | BRN 5354948 | C20H32N2O2S2 | 396.608 | 6 / 0 | 3.2 | Yes |
298626 | RS-86 | C11H19BrN2O2 | 291.189 | 3 / 1 | N/A | N/A |
302877 | CHEMBL544767 | C9H15ClN2O3 | 234.68 | 4 / 1 | N/A | N/A |
303757 | Oxotremorine | C12H18N2O | 206.289 | 2 / 0 | 0.4 | Yes |
306443 | BRN 5363156 | C30H36N2O2S2 | 520.75 | 6 / 0 | 5.4 | No |
324390 | CHEMBL555730 | C9H15ClN2O3 | 234.68 | 4 / 2 | N/A | N/A |
359640 | SCHEMBL8307259 | C9H11F3N4O3 | 280.207 | 9 / 2 | N/A | N/A |
360946 | Carbamylcholine | C6H15N2O2+ | 147.198 | 2 / 1 | -0.4 | Yes |
368567 | CHEMBL553123 | C8H13ClN2O2S | 236.714 | 4 / 2 | N/A | N/A |
382353 | CHEMBL419451 | C11H16N2O3 | 224.26 | 4 / 0 | 0.7 | Yes |
401042 | CHEMBL306839 | C10H15N3O4 | 241.247 | 5 / 1 | -1.0 | Yes |
413002 | Tacrine | C13H14N2 | 198.269 | 2 / 1 | 2.7 | Yes |
435495 | BRN 5356615 | C22H36N2O2S2 | 424.662 | 6 / 0 | 3.9 | Yes |
440556 | BRN 5353847 | C19H30N2O2S2 | 382.581 | 6 / 0 | 2.8 | Yes |
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