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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BRN 5365697
Molecular formula	C22H34N6O2S2
IUPAC name	1-cyano-2,3-bis[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]guanidine
Molecular weight	478.674
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	1.8
Synonyms	N"-Cyano-N,N'-bis[2-[[5-[(dimethylamino)methyl]-2-furanylmethyl]thio]ethyl]guanidine DTXSID20222469 SCHEMBL11210377 BDBM50005493 LPWXASFIPNYFQP-UHFFFAOYSA-N 1,3-Bis[2-[[5-(dimethylaminomethyl)-2-furanyl]methylthio]ethyl]-2-cyanoguanidine CHEMBL12858 N-((5-Ethylsulfanylmethyl-furan-2-ylmethyl)-dimethyl-amine)l-N-[1-(((5-Ethylsulfanylmethyl-furan-2-ylmethyl)-dimethyl-amine)amino)-2-cynovinyl]amine 72148-12-0 Guanidine, N-cyano-N',N''-bis(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)- LS-73393 1-cyano-2,3-bis[2-[[5-(dimethylaminomethyl)furan-2-yl]methylsulfanyl]ethyl]guanidine CTK5D5620 N-Cyano-N',N''-bis(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)guanidine AC1MHP57 Guanidine,N-cyano-N',N''-bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]- [ Show all ]
Inchi Key	LPWXASFIPNYFQP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H34N6O2S2/c1-27(2)13-18-5-7-20(29-18)15-31-11-9-24-22(26-17-23)25-10-12-32-16-21-8-6-19(30-21)14-28(3)4/h5-8H,9-16H2,1-4H3,(H2,24,25,26)
PubChem CID	3055247
ChEMBL	CHEMBL12858
IUPHAR	N/A
BindingDB	50005493
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
193480	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
193481	Muscarinic acetylcholine receptor M2	Q9ERZ4	Chrm2	Mus musculus (Mouse)	466

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