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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL74823
Molecular formula	C14H15ClN2O3
IUPAC name	3-(3-chlorophenyl)-8-methyl-1-oxa-3,8-diazaspiro[4.5]decane-2,4-dione
Molecular weight	294.735
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.3
Synonyms	3-(3-chlorophenyl)-8-methyl-1-oxa-3,8-diazaspiro[4.5]decane-2,4-dione 3-(3-Chloro-phenyl)-8-methyl-1-oxa-3,8-diaza-spiro[4.5]decane-2,4-dione BDBM50044694
Inchi Key	CANVZWCREHESOT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H15ClN2O3/c1-16-7-5-14(6-8-16)12(18)17(13(19)20-14)11-4-2-3-10(15)9-11/h2-4,9H,5-8H2,1H3
PubChem CID	14956875
ChEMBL	CHEMBL74823
IUPHAR	N/A
BindingDB	50044694
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37357	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
37358	Muscarinic acetylcholine receptor M2	Q9ERZ4	Chrm2	Mus musculus (Mouse)	466

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