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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BRN 5358078
Molecular formula	C24H40N2O2S2
IUPAC name	1-[5-[8-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]octylsulfanylmethyl]furan-2-yl]-N,N-dimethylmethanamine
Molecular weight	452.716
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.0
Synonyms	AC1MIKNI 138878-48-5 5,5'-(1,8-Octanediylbis(thiomethylene))bis(N,N-dimethyl-2-furanmethanamine) LS-70245 BDBM50005494 2,2'-[1,8-Octanediylbis(thiomethylene)]bis[5-(dimethylaminomethyl)furan] CHEMBL418714 {5-[8-(5-Dimethylaminomethyl-furan-2-ylmethylsulfanyl)-octylsulfanylmethyl]-furan-2-ylmethyl}-dimethyl-amine 1-[5-[8-[[5-(dimethylaminomethyl)furan-2-yl]methylsulfanyl]octylsulfanylmethyl]furan-2-yl]-N,N-dimethylmethanamine 2-Furanmethanamine, 5,5'-(1,8-octanediylbis(thiomethylene))bis(N,N-dimethyl- DTXSID90160829 [ Show all ]
Inchi Key	CINOACUWPXQJTR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H40N2O2S2/c1-25(2)17-21-11-13-23(27-21)19-29-15-9-7-5-6-8-10-16-30-20-24-14-12-22(28-24)18-26(3)4/h11-14H,5-10,15-20H2,1-4H3
PubChem CID	3071777
ChEMBL	CHEMBL418714
IUPHAR	N/A
BindingDB	50005494
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42823	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
42822	Muscarinic acetylcholine receptor M2	Q9ERZ4	Chrm2	Mus musculus (Mouse)	466

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