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| Name | Neuropeptide Y receptor type 2 |
|---|---|
| Species | Homo sapiens (Human) |
| Gene | NPY2R |
| Synonym | NPY2-R NPY-Y2 receptor neuropeptide Y receptor type 2 Y2 receptor |
| Disease | Diabetes Metabolic disorders Obesity |
| Length | 381 |
| Amino acid sequence | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV |
| UniProt | P49146 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | P49146 |
| 3D structure model | This predicted structure model is from GPCR-EXP P49146. |
| BioLiP | N/A |
| Therapeutic Target Database | T10670 |
| ChEMBL | CHEMBL4018 |
| IUPHAR | 306 |
| DrugBank | BE0002419 |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 338 |  BDBM50442547 | C104H138N24O15 | 1964.4 | 20 / 19 | 6.9 | No |
| 686 |  SMR000091760 | C20H15N5O3S | 405.432 | 7 / 0 | 2.8 | Yes |
| 1186 |  CHEMBL3104204 | C29H36FN5O3 | 521.637 | 7 / 1 | 3.9 | No |
| 1540 |  CHEMBL1288285 | C29H35ClF3N3O | 534.064 | 6 / 1 | 6.8 | No |
| 1559 |  hexachlorophene | C13H6Cl6O2 | 406.889 | 2 / 2 | 7.5 | No |
| 2016 |  MLS000053810 | C21H22N2O5 | 382.416 | 5 / 1 | 2.7 | Yes |
| 2346 |  CID 16147801 | C91H140N30O21 | 1990.31 | 26 / 33 | -3.7 | No |
| 3108 |  CHEMBL100162 | C26H26N2OS2 | 446.627 | 4 / 1 | 6.2 | No |
| 3870 |  MLS000041001 | C17H19N3O | 281.359 | 4 / 0 | 4.2 | Yes |
| 3941 |  CHEMBL2030161 | C28H30N2O3S | 474.619 | 4 / 2 | 5.0 | Yes |
| 463407 |  CHEMBL3578011 | C87H143N29O20 | 1915.28 | 25 / 31 | -2.9 | No |
| 4630 |  MLS000724783 | C18H18ClF2N3O2S2 | 445.928 | 6 / 1 | 4.1 | Yes |
| 4745 |  CHEMBL1823359 | C36H37N5O2 | 571.725 | 5 / 1 | 6.0 | No |
| 4785 |  CHEMBL561577 | C23H26ClN3O3 | 427.929 | 4 / 1 | 3.5 | Yes |
| 5147 |  CHEMBL1823343 | C31H30N4O3 | 506.606 | 6 / 1 | 4.9 | No |
| 557424 |  MLS000060886 | C20H16N2O2 | 316.36 | 3 / 2 | 4.0 | Yes |
| 6058 |  CHEMBL3104183 | C27H34FN5O2 | 479.6 | 7 / 0 | 5.0 | Yes |
| 6929 |  CHEMBL2403026 | C30H35FN4O2 | 502.634 | 4 / 3 | 5.5 | No |
| 7267 |  CHEMBL3104176 | C27H34FN5O2 | 479.6 | 7 / 1 | 5.2 | No |
| 7671 |  CHEMBL1288138 | C24H32ClN3O | 413.99 | 3 / 2 | 5.3 | No |
| 7915 |  CHEMBL349328 | C38H49IN4O2 | 720.74 | 5 / 0 | 8.2 | No |
| 7932 |  MLS000083032 | C16H12Cl2N6S | 391.274 | 5 / 1 | 3.9 | Yes |
| 8868 |  MLS000072668 | C26H35ClN6O3 | 515.055 | 8 / 1 | N/A | No |
| 8874 |  CID 73351118 | C184H287N53O53S2 | 4153.76 | 61 / 58 | -13.6 | No |
| 9137 |  CHEMBL3104125 | C27H34FN5O2 | 479.6 | 7 / 1 | 5.2 | No |
| 9242 |  CID 76335489 | C177H272N52O55 | 4008.43 | 62 / 60 | -15.6 | No |
| 9271 |  2-[4-(2-methoxyphenoxy)-3-nitrophenyl]quinoxaline | C21H15N3O4 | 373.368 | 6 / 0 | 4.2 | Yes |
| 9310 |  MLS000778774 | C21H18N2O4S2 | 426.505 | 7 / 1 | 4.2 | Yes |
| 9588 |  CHEMBL2370632 | C97H155N33O26 | 2199.51 | 32 / 33 | -10.1 | No |
| 9970 |  67572-43-4 | C11H8N2O5S | 280.254 | 8 / 1 | 1.7 | Yes |
| 10004 |  BDBM50003047 | C108H163N35O28 | 2399.71 | 34 / 41 | -6.2 | No |
| 10297 |  SMR000163162 | C23H19F3N2O5 | 460.409 | 8 / 1 | 5.1 | No |
| 10533 |  CHEMBL3104211 | C29H39FN4O2 | 494.655 | 5 / 1 | 5.2 | No |
| 10607 |  CHEMBL288355 | C28H33N5O3 | 487.604 | 4 / 5 | 2.9 | Yes |
| 10627 |  CHEMBL3104187 | C28H37FN6O | 492.643 | 6 / 0 | 4.8 | Yes |
| 11433 |  MLS000705653 | C17H26N2O4S | 354.465 | 5 / 2 | 2.8 | Yes |
| 11436 |  CHEMBL42747 | C30H35N5O3 | 513.642 | 4 / 4 | 3.1 | No |
| 12146 |  Ac-Peptide YY(25-36) | C74H118N26O18 | 1659.92 | 37 / 31 | 4.7 | No |
| 13870 |  CHEMBL2440903 | C41H56N12O7 | 828.976 | 9 / 11 | -1.2 | No |
| 14042 |  MLS000685650 | C16H12N2O3S2 | 344.403 | 6 / 3 | 4.1 | Yes |
| 14630 |  D0P9KP | C180H279N53O54 | 4049.53 | 61 / 61 | -14.9 | No |
| 15149 |  MLS000570445 | C25H20N2O3 | 396.446 | 4 / 1 | 4.8 | Yes |
| 15168 |  CHEMBL21992 | C31H31N3O3 | 493.607 | 3 / 0 | 4.5 | Yes |
| 15875 |  MLS000114342 | C18H18ClNO3 | 331.796 | 3 / 0 | 2.2 | Yes |
| 17138 |  CHEMBL2440659 | C15H11FN4O2S | 330.337 | 7 / 1 | 2.4 | Yes |
| 17340 |  MLS000585997 | C22H24N2O3S2 | 428.565 | 5 / 2 | 5.1 | No |
| 17775 |  MLS000552453 | C15H18Cl2N4O2S | 389.295 | 7 / 0 | 4.9 | Yes |
| 17854 |  MLS000807054 | C12H17NO6 | 271.269 | 7 / 2 | -2.6 | Yes |
| 557824 |  SMR000047897 | C17H16N2O4 | 312.325 | 5 / 3 | 3.1 | Yes |
| 18584 |  SMR000221562 | C18H23N3S | 313.463 | 4 / 0 | 3.8 | Yes |
| 18660 |  MLS000771330 | C20H17FN2O4 | 368.364 | 6 / 0 | 2.4 | Yes |
| 18940 |  CHEMBL1287899 | C22H25ClFN3O2 | 417.909 | 4 / 1 | 4.3 | Yes |
| 19831 |  AC1LCZE6 | C20H19Cl2N3O2 | 404.291 | 4 / 3 | N/A | N/A |
| 20745 |  32D-W-NPY | C196H288N56O56S | 4356.86 | 64 / 59 | -15.3 | No |
| 20950 |  SMR000140824 | C15H12Cl3N3O | 356.631 | 3 / 2 | 5.6 | No |
| 21631 |  CID 44346875 | C104H168N34O27 | 2326.7 | 33 / 34 | -8.4 | No |
| 22037 |  MLS000089771 | C23H30N2O2 | 366.505 | 4 / 1 | 4.3 | Yes |
| 522133 |  CHEMBL3775436 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 522205 |  CHEMBL3775769 | C15H26ClNO3 | 303.827 | 4 / 3 | N/A | N/A |
| 23208 |  CHEMBL3104220 | C26H31N3O2 | 417.553 | 3 / 0 | 3.6 | Yes |
| 23371 |  CHEMBL311159 | C23H23N3O5 | 421.453 | 5 / 2 | 3.7 | Yes |
| 23395 |  SMR000117962 | C24H25N5O4S | 479.555 | 8 / 1 | 3.2 | Yes |
| 23748 |  CHEMBL585711 | C22H26FN5OS2 | 459.602 | 9 / 1 | 3.8 | Yes |
| 23764 |  CHEMBL549895 | C23H25ClF3N3O2 | 467.917 | 6 / 1 | 5.1 | No |
| 24073 |  CHEMBL3104198 | C28H37F3N4O2 | 518.625 | 7 / 1 | 5.0 | No |
| 24259 |  BDBM50046541 | C151H233N45O40 | 3318.8 | 47 / 50 | -11.0 | No |
| 24518 |  CHEMBL2030159 | C26H28N2O2S | 432.582 | 3 / 2 | 4.8 | Yes |
| 25224 |  Neuropeptide Y(NPY)(13-36) | C135H208N40O37 | 2983.39 | 43 / 48 | -5.9 | No |
| 25401 |  MLS002589217 | C22H21N3O5 | 407.426 | 6 / 2 | 3.9 | Yes |
| 25636 |  CHEMBL410502 | C163H249N48O42+ | 3553.08 | 49 / 51 | -9.1 | No |
| 27200 |  CHEMBL2203713 | C18H22N4S | 326.462 | 4 / 2 | 2.9 | Yes |
| 27241 |  SMR000264080 | C23H18ClNO3 | 391.851 | 3 / 1 | 5.4 | No |
| 27382 |  MLS000032393 | C26H26N6O3 | 470.533 | 7 / 1 | 2.9 | Yes |
| 28188 |  CHEMBL556481 | C30H27ClN4O2 | 511.022 | 4 / 1 | 5.0 | No |
| 29067 |  CHEMBL3104212 | C27H35FN4O2 | 466.601 | 5 / 1 | 4.1 | Yes |
| 29543 |  CHEMBL1288078 | C27H33ClF3N3O | 508.026 | 6 / 1 | 6.7 | No |
| 29550 |  CID 77114776 | C190H286N54O58 | 4254.7 | 65 / 59 | -16.4 | No |
| 30143 |  MLS000712137 | C19H21N5O3S | 399.469 | 7 / 1 | 3.3 | Yes |
| 30517 |  MLS000677133 | C20H26ClN3O5 | 423.894 | 7 / 2 | N/A | N/A |
| 30978 |  MLS000569792 | C19H19N3OS | 337.441 | 3 / 2 | 4.0 | Yes |
| 31603 |  CID 44439571 | C81H123N27O18 | 1763.05 | 23 / 29 | -2.0 | No |
| 558290 |  MLS000760186 | C18H19ClN2O3S | 378.871 | 5 / 2 | 3.5 | Yes |
| 33416 |  3-Methyl-5-nitro-1H-indole-2-carboxylic acid | C10H8N2O4 | 220.184 | 4 / 2 | 2.1 | Yes |
| 33478 |  UNII-7W7511NPF8 | C20H20N2O3S | 368.451 | 6 / 1 | 1.8 | Yes |
| 33510 |  CHEMBL2030191 | C26H27NO5S | 465.564 | 5 / 1 | 4.0 | Yes |
| 33839 |  CHEMBL77589 | C24H26N2O2 | 374.484 | 2 / 1 | 5.6 | No |
| 34243 |  CHEMBL21507 | C32H41N3O2 | 499.699 | 3 / 0 | 6.4 | No |
| 34412 |  CHEMBL95327 | C27H27N3O2S | 457.592 | 4 / 1 | 5.5 | No |
| 34641 |  BDBM50046546 | C104H162N32O26 | 2276.64 | 32 / 35 | -6.3 | No |
| 34799 |  MLS000582311 | C28H26N2O3S | 470.587 | 4 / 2 | 6.0 | No |
| 34976 |  CHEMBL2030179 | C26H30N4O3S2 | 510.671 | 6 / 2 | 2.9 | No |
| 35087 |  CHEMBL1774211 | C57H65F3N8O7 | 1031.19 | 12 / 6 | N/A | No |
| 35347 |  CHEMBL1288227 | C24H29ClF3N5O | 495.975 | 8 / 2 | 4.5 | Yes |
| 35828 |  MolPort-000-720-960 | C17H27BrN2 | 339.321 | 2 / 1 | N/A | N/A |
| 36073 |  CHEMBL21605 | C31H31F2N3O2 | 515.605 | 5 / 0 | 5.0 | No |
| 36603 |  BDBM61808 | C22H21N3O5 | 407.426 | 6 / 4 | 5.3 | No |
| 37552 |  CHEMBL3104207 | C34H41FN4O2 | 556.726 | 5 / 1 | 6.1 | No |
| 37704 |  CHEMBL3040658 | C84H116N18O16 | 1633.96 | 18 / 17 | 2.5 | No |
| 37964 |  CHEMBL279236 | C30H31N3O2 | 465.597 | 3 / 0 | 4.9 | Yes |
| 38216 |  CHEMBL123410 | C22H24Cl2N2O | 403.347 | 2 / 0 | 5.4 | No |
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