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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Neuropeptide Y receptor type 2
Species	Homo sapiens (Human)
Gene	NPY2R
Synonym	NPY2-R NPY-Y2 receptor neuropeptide Y receptor type 2 Y2 receptor
Disease	Diabetes Metabolic disorders Obesity
Length	381
Amino acid sequence	MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
UniProt	P49146
Protein Data Bank	N/A
GPCR-HGmod model	P49146
3D structure model	This predicted structure model is from GPCR-EXP P49146.
BioLiP	N/A
Therapeutic Target Database	T10670
ChEMBL	CHEMBL4018
IUPHAR	306
DrugBank	BE0002419

Ligand

Name	CHEMBL77589
Molecular formula	C24H26N2O2
IUPAC name	1-methyl-3-(4-phenoxyphenyl)-1-(1-phenylbutan-2-yl)urea
Molecular weight	374.484
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.6
Synonyms	1-(1-Benzyl-propyl)-1-methyl-3-(4-phenoxy-phenyl)-urea BDBM50101546 1-(1-Benzylpropyl)-1-methyl-3-(4-phenoxyphenyl)urea
Inchi Key	BVLBVQUFUDMCEW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N2O2/c1-3-21(18-19-10-6-4-7-11-19)26(2)24(27)25-20-14-16-23(17-15-20)28-22-12-8-5-9-13-22/h4-17,21H,3,18H2,1-2H3,(H,25,27)
PubChem CID	11760541
ChEMBL	CHEMBL77589
IUPHAR	N/A
BindingDB	50101546
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<10000.0 nM	PMID11428928	BindingDB,ChEMBL

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