You can:
| Name | Nociceptin receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Oprl1 |
| Synonym | NOP receptor NOP-r NOPr OP4 Orphanin FQ receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 367 |
| Amino acid sequence | MESLFPAPYWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASSLHREMQVSDRVRSIAKDVGLGCKTSETVPRPA |
| UniProt | P35370 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL4503 |
| IUPHAR | 320 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 5386 |  CHEMBL353990 | C21H31N3O | 341.499 | 3 / 1 | 4.2 | Yes |
| 11646 |  CHEMBL2403216 | C50H71N15O10 | 1042.21 | 13 / 15 | -1.2 | No |
| 19657 |  CHEMBL355202 | C25H25N3O | 383.495 | 3 / 1 | 4.5 | Yes |
| 21278 |  BDBM50274467 | C85H133N27O23 | 1901.17 | 28 / 29 | -9.7 | No |
| 553474 |  Cebranopadol | C24H27FN2O | 378.491 | 3 / 1 | 4.3 | Yes |
| 55045 |  CHEMBL186795 | C30H33F3N2O2 | 510.601 | 6 / 1 | 5.3 | No |
| 55220 |  CHEMBL196932 | C26H21BrN2O4 | 505.368 | 4 / 0 | 4.3 | No |
| 55454 |  CHEMBL194442 | C29H22BrNO3 | 512.403 | 3 / 0 | 6.7 | No |
| 61692 |  D05EUV | C82H137N33O22 | 1937.21 | 29 / 36 | -13.2 | No |
| 75865 |  CHEMBL427954 | C55H88N22O15 | 1297.45 | 20 / 22 | -9.1 | No |
| 82308 |  D0H7NY | C76H123N27O22 | 1766.99 | 27 / 30 | -11.5 | No |
| 82691 |  CID 100916438 | C79H130N28O21 | 1808.08 | 45 / 33 | 2.1 | No |
| 89610 |  CHEMBL365101 | C19H20BrNO2 | 374.278 | 3 / 0 | 3.9 | Yes |
| 89616 |  CHEMBL193614 | C19H20BrNO2 | 374.278 | 3 / 0 | 3.9 | Yes |
| 93478 |  OFQ/N UFP-102 | C73H123FN28O17 | 1683.96 | 25 / 27 | -8.8 | No |
| 106292 |  UFP-112 | C83H139FN32O21 | 1940.23 | 29 / 34 | -10.7 | No |
| 106800 |  CHEMBL83326 | C17H19NO3S | 317.403 | 4 / 4 | 2.5 | Yes |
| 107073 |  CHEMBL354291 | C23H35N3O | 369.553 | 3 / 1 | 5.2 | No |
| 111451 |  D0SG5A | C87H135N31O22 | 1967.23 | 28 / 34 | -10.6 | No |
| 121033 |  CHEMBL354652 | C25H39N3O | 397.607 | 3 / 1 | 6.3 | No |
| 128751 |  CHEMBL440928 | C22H33N3O | 355.526 | 3 / 1 | 4.7 | Yes |
| 143861 |  D0C1US | C87H134N28O22 | 1924.2 | 27 / 31 | -8.5 | No |
| 154645 |  CHEMBL370780 | C26H22BrNO5 | 508.368 | 5 / 0 | 5.4 | No |
| 165951 |  D08ZIR | C85H133N27O22 | 1885.17 | 27 / 30 | -8.6 | No |
| 175928 |  CHEMBL364625 | C29H30F3NO3 | 497.558 | 7 / 1 | 5.7 | No |
| 178282 |  CHEMBL194994 | C19H21NO2 | 295.382 | 3 / 0 | 3.2 | Yes |
| 178291 |  CHEMBL330713 | C19H21NO2 | 295.382 | 3 / 0 | 3.2 | Yes |
| 178292 |  SCHEMBL5945733 | C19H21NO2 | 295.382 | 3 / 0 | 3.2 | Yes |
| 178306 |  D09ZTU | C87H135N31O22 | 1967.23 | 28 / 34 | -10.6 | No |
| 183738 |  BDBM50411363 | C83H140N32O21 | 1922.24 | 28 / 31 | -11.9 | No |
| 186679 |  CHEMBL197135 | C19H20FNO2 | 313.372 | 4 / 0 | 3.3 | Yes |
| 186691 |  CHEMBL362950 | C19H20FNO2 | 313.372 | 4 / 0 | 3.3 | Yes |
| 188278 |  BDBM50274452 | C82H137N31O22 | 1909.19 | 29 / 31 | -13.7 | No |
| 554244 |  SCH 221510 | C28H31NO | 397.562 | 2 / 1 | 6.0 | No |
| 205473 |  CHEMBL373174 | C24H20BrNO3 | 450.332 | 3 / 0 | 5.4 | No |
| 205522 |  CHEMBL363622 | C24H17BrN2O3 | 461.315 | 4 / 0 | 4.9 | Yes |
| 212065 |  CHEMBL405645 | C60H98N22O15 | 1367.58 | 20 / 22 | -7.3 | No |
| 212587 |  BDBM50274461 | C84H128N28O22 | 1882.12 | 27 / 29 | -10.6 | No |
| 232129 |  CID 102330627 | C82H127N27O23 | 1859.08 | 46 / 33 | -0.4 | No |
| 232840 |  CHEMBL186300 | C28H30ClNO3 | 464.002 | 4 / 1 | 5.4 | No |
| 245664 |  D07HZU | C81H133N27O22 | 1837.12 | 27 / 30 | -9.3 | No |
| 247456 |  D09POP | C85H143N31O21 | 1935.28 | 28 / 33 | -10.2 | No |
| 247547 |  D06ZTU | C82H135N27O22 | 1851.15 | 27 / 30 | -8.9 | No |
| 253650 |  BDBM50274456 | C79H130N28O22 | 1824.08 | 28 / 29 | -12.5 | No |
| 256878 |  CHEMBL322515 | C27H28F3NO | 439.522 | 5 / 1 | 6.1 | No |
| 258021 |  CHEMBL372244 | C27H25BrN2O4 | 521.411 | 5 / 0 | 5.0 | No |
| 262470 |  BDBM50274458 | C78H127N27O22 | 1795.04 | 27 / 28 | -11.3 | No |
| 264650 |  D07KNS | C82H136N28O22 | 1866.16 | 28 / 31 | -10.5 | No |
| 269184 |  BDBM21842 | C79H129N27O22 | 1809.07 | 27 / 28 | -11.0 | No |
| 272626 |  CHEMBL442305 | C60H98N22O15 | 1367.58 | 20 / 22 | -7.3 | No |
| 278270 |  CHEMBL437744 | C84H142FN33O21 | 1969.27 | 30 / 32 | -12.7 | No |
| 278273 |  CHEMBL2372052 | C84H142FN33O21 | 1969.27 | 30 / 35 | -11.6 | No |
| 292565 |  CHEMBL370607 | C23H19BrN2O3 | 451.32 | 4 / 1 | 4.5 | Yes |
| 295255 |  CHEMBL165885 | C20H29N3O | 327.472 | 3 / 1 | 3.6 | Yes |
| 296316 |  nociceptin(1-13)NH2 | C61H100N22O15 | 1381.61 | 20 / 22 | -7.0 | No |
| 296430 |  CHEMBL363619 | C19H20ClNO2 | 329.824 | 3 / 0 | 3.8 | Yes |
| 296441 |  CHEMBL371207 | C19H20ClNO2 | 329.824 | 3 / 0 | 3.8 | Yes |
| 298287 |  CHEMBL263575 | C19H27N3O | 313.445 | 3 / 1 | 3.1 | Yes |
| 298620 |  CHEMBL186426 | C26H28ClNO | 405.966 | 2 / 1 | 5.8 | No |
| 303949 |  CHEMBL381000 | C28H27BrN2O4 | 535.438 | 5 / 0 | 4.5 | No |
| 310047 |  CHEMBL219144 | C59H96N22O15 | 1353.56 | 20 / 22 | -7.7 | No |
| 318857 |  D07ZFH | C86H145N31O22 | 1965.3 | 29 / 34 | -10.9 | No |
| 328899 |  CHEMBL170674 | C28H45N3O | 439.688 | 3 / 1 | 7.9 | No |
| 334330 |  BDBM50274454 | C82H137N29O22 | 1881.18 | 29 / 30 | -12.8 | No |
| 335887 |  CHEMBL427007 | C25H23BrN2O3 | 479.374 | 4 / 0 | 5.3 | No |
| 338224 |  BDBM50274451 | C85H147N33O20 | 1951.32 | 29 / 32 | -12.5 | No |
| 340913 |  FGGFTGARKSARKLARK | C73H130N28O19 | 1704.02 | 26 / 28 | -11.1 | No |
| 344092 |  BDBM50296844 | C87H135N29O22 | 1939.22 | 28 / 30 | -10.8 | No |
| 347276 |  CHEMBL1783826 | C26H33Cl2N3O | 474.47 | 3 / 1 | 5.5 | No |
| 364615 |  BDBM50274449 | C82H137N31O22 | 1909.19 | 29 / 31 | -13.7 | No |
| 371331 |  CHEMBL186938 | C29H29ClF3NO3 | 532.0 | 7 / 1 | 6.3 | No |
| 382121 |  CHEMBL371984 | C20H23NO3 | 325.408 | 4 / 0 | 3.2 | Yes |
| 382125 |  CHEMBL381664 | C20H23NO3 | 325.408 | 4 / 0 | 3.2 | Yes |
| 382904 |  CHEMBL325536 | C27H27ClF3NO | 473.964 | 5 / 1 | 6.7 | No |
| 385843 |  CHEMBL354545 | C24H37N3O | 383.58 | 3 / 1 | 5.8 | No |
| 387406 |  BDBM50274459 | C82H127N27O22 | 1843.08 | 27 / 28 | -10.7 | No |
| 390016 |  BDBM86252 | C146H235N49O42S2 | 3412.91 | 50 / 51 | -17.4 | No |
| 417538 |  Ac-RYYRWK-NH2 | C49H69N15O9 | 1012.19 | 12 / 15 | -1.3 | No |
| 418896 |  D0L3JC | C79H130N30O22 | 1852.1 | 28 / 33 | -12.4 | No |
| 420891 |  D0BH3Y | C82H136N30O22 | 1894.18 | 28 / 33 | -11.0 | No |
| 433190 |  CHEMBL111233 | C23H21ClF3NO | 419.872 | 5 / 1 | 5.7 | No |
| 440227 |  BDBM50296842 | C87H135N29O22 | 1939.22 | 28 / 30 | -10.8 | No |
zhanglab
zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417